Treatment of endotoxinemia syndrome in patients with atopic dermatitis

Yu S Fedorova , V Yu Vasenova , Yu S Butov , Yu S Fyodorova , V Yu Vasyonova , Yu S Butov

Russian Journal of Skin and Venereal Diseases ›› 2011, Vol. 14 ›› Issue (1) : 16 -20.

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Russian Journal of Skin and Venereal Diseases ›› 2011, Vol. 14 ›› Issue (1) : 16 -20. DOI: 10.17816/dv36504
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Treatment of endotoxinemia syndrome in patients with atopic dermatitis

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Abstract

The role of endotoxin in pathogenesis of atopic dermatitis (AD) is discussed. A total of 81 patients with AD were examined (68 men and 13 women from 16 to 53 years old). In 60% of patients disorders of gastro-intestinal tract were diagnosed, in 90% of subjects disbalance of gastrointestinal microflora was detected. In all patients mean level of endotoxin (lipopolyssacharide) in blood was above normal. A pathogenetic method of AD treatment is suggested including enterosorbents, probiotics, and hepatoprotectors.

Keywords

atopic dermatitis / endotoxin / endotoxin aggression / antiendotoxin therapy

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Yu S Fedorova, V Yu Vasenova, Yu S Butov, Yu S Fyodorova, V Yu Vasyonova, Yu S Butov. Treatment of endotoxinemia syndrome in patients with atopic dermatitis. Russian Journal of Skin and Venereal Diseases, 2011, 14(1): 16-20 DOI:10.17816/dv36504

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