Progressing radiation injury of the rectum. Clinical observation
T. E. Skvortsova , I. А. Oganezova
Medical and Social Expert Evaluation and Rehabilitation ›› 2020, Vol. 23 ›› Issue (3) : 31 -36.
Progressing radiation injury of the rectum. Clinical observation
Radiation damage to the rectum is the most common complication in radiation therapy of malignancies of pelvic organs. Clinical manifestations of chronic radiation proctitis can occur both 3 months after completion of therapy and decades later. Late radiation injuries to the intestine often has a persistent course, drug treatment is prolonged and repeated, in severe cases surgical treatment is required. The article presents literature data on pathophysiology, clinical picture, diagnostics and possibilities of treating this pathology. A clinical case reflecting the progressive course of the disease is described.
radiation proctitis / the progressing radiation injury / complications of the radiation proctitis
| [1] |
Reddy VJ, Sureshkumar S, Vijayakumar C, et al. Concurrent chemoradiation affects the clinical outcome of small bowel complications following pelvic irradiation: prospective observational study from a regional cancer center. Cureus. 2018;10(3):e2317. https://doi.org/10.7759/cureus.2317. |
| [2] |
Mallick S, Madan R, Julka PK, Rath GK. Radiation induced cystitis and proctitis − prediction, assessment and management. Asian Pac J Cancer Prev. 2015;16(14):5589−5594. |
| [3] |
https://doi.org/10.7314/apjcp.2015.16.14.5589. |
| [4] |
Wu XR, Liu XL, Katz S, Shen B. Pathogenesis, diagnosis, and management of ulcerative proctitis, chronic radiation proctopathy, and diversion proctitis. Inflamm Bowel Dis. 2015;21(3):703−715. https://doi.org/10.1097/MIB.0000000000000227. |
| [5] |
Сычева И.В. Лечение лучевых повреждений органов малого таза после лучевой терапии рака предстательной железы // Сибирский онкологический журнал. ― 2018. ― Т.17. ― №3. ― С. 64–71. [Sycheva IV. Treatment of radiation-induced pelvic damage after radiation therapy for prostate cancer. Siberian Journal of Oncology. 2018;17(3):64–71. (In Russ).] |
| [6] |
https://doi.org/10.21294/1814-4861-2018-17-3-64-71. |
| [7] |
Mendenhall WM, McKibben BT, Hoppe BS, et al. Management of radiation proctitis. Am J Clin Oncol. 2014;37(5):517–523. https://doi.org/10.1097/COC.0b013e318271b1aa. |
| [8] |
Гречин А.И., Пикунов Д.Ю., Майновская О.А., и др. Хронический лучевой проктит. Современные возможности диагностики и лечения (обзор литературы) // Колопроктология. ― 2018. ― №3. ― С. 66−74. [Grechin AN, Pikunov DY, Mainovskaya OA, et al. Chronic radiation proctitis. Modern opportunities of diagnosis and treatment (review). Koloproktologia. 2018;(3):66−74. (In Russ.)] |
| [9] |
https://doi.org/10.33878/2073-7556-2018-0-3-66-74. |
| [10] |
Lenz L, Rohr R, Nakao F, et al. Chronic radiation proctopathy: A practical review of endoscopic treatment. World J Gastrointest Surg. 2016;8(2):151–160. |
| [11] |
https://doi.org/10.4240/wjgs.v8.i2.151. |
| [12] |
Sarin A, Safar B. Management of radiation proctitis. Gastroenterol Clin North Am. 2013;42(4):913–925. |
| [13] |
https://doi.org/10.1016/j.gtc.2013.08.004. |
| [14] |
Бакулин И.Г., Авалуева Е.Б., Сказываева Е.В., и др. Карманные рекомендации для врачей по ведению пациентов с воспалительными заболеваниями кишечника. ― М.: Группа Ремедиум, 2018. ― 80 с. [Bakulin IG, Avalueva EB, Skazyvaeva EV, et al. Karmannyye rekomendatsii dlya vrachey po vedeniyu patsiyentov s vospalitel’nymi zabolevaniyami kishechnika. Moscow: Gruppa Remedium; 2018. 80 p. (In Russ.)] |
| [15] |
Ramakrishnaiah VP, Krishnamachari S. Chronic haemorrhagic radiation proctitis: A review. World J Gastrointest Surg. 2016;8(7):483–491. https://doi.org/10.4240/wjgs.v8.i7.483. |
| [16] |
Vanneste BG, van de Voorde L, de Ridder RJ, et al. Chronic radiation proctitis: tricks to prevent and treat. Int J Colorectal Dis. 2015;30(10):1293–1303. |
| [17] |
https://doi.org/10.1007/s00384-015-2289-4. |
| [18] |
Chruscielewska-Kiliszek MR, Regula J, Polkowski M, et al. Sucralfate or placebo following argon plasma coagulation for chronic radiation proctitis: a randomized double blind trial. Colorectal Dis. 2013;15(1):e48–e55. https://doi.org/10.1111/codi.12035. |
| [19] |
Porouhan P, Farshchian N, Dayani M. Management of radiation-induced proctitis. J Family Med Prim Care. 2019;8(7):2173–2178. https://doi.org/10.4103/jfmpc.jfmpc_333_19. |
| [20] |
Tabaja L, Sidani SM. Management of radiation proctitis. Dig Dis Sci. 2018;63(9):2180−2188. |
| [21] |
https://doi.org/10.1007/s10620-018-5163-8. |
| [22] |
Lam MC, Parliament M, Wong CK. Argon plasma coagulation for the treatment of hemorrhagic radiation colitis. Case Rep Gastroenterol. 2012;6(2):446–451. https://doi.org/10.1159/000339462. |
| [23] |
Peng Y, Wang H, Feng J, et al. Efficacy and safety of argon plasma coagulation for hemorrhagic chronic radiation proctopathy: a systematic review. Gastroenterol Res Pract. 2018;2018:3087603 https://doi.org/10.1155/2018/3087603. |
| [24] |
Do NL, Nagle D, Poylin VY. Radiation proctitis: current strategies in management. Gastroenterol Res Pract. 2011;2011:917941. https://doi.org/10.1155/2011/917941. |
| [25] |
Van de Wetering FT, Verleye L, Andreyev HJ, et al. Non-surgical interventions for late rectal problems (proctopathy) of radiotherapy in people who have received radiotherapy to the pelvis. Cochrane Database Syst Rev. 2016;4(4):CD003455. |
| [26] |
https://doi.org/10.1002/14651858.CD003455.pub2. |
| [27] |
Weiner JP, Wong AT, Schwartz D, et al. Endoscopic and non-endoscopic approaches for the management of radiation-induced rectal bleeding. World J Gastroenterol. 2016;22(31):6972–6986. https://doi.org/10.3748/wjg.v22.i31.6972. |
Eco-Vector
/
| 〈 |
|
〉 |