Disorders of mental and statodynamic functions from the toxic effects of mercury and its compounds in patients aged 18 years and older in the Republic of Mordovia Mordovia for the period 2015–2020

Abstract

BACKGROUND: The importance of studying the toxic effects of mercury and its compounds in patients aged 18 years and older is due to the continuing high levels of disability and loss of the professional ability to work (PAW). An analysis of the indicators of acute and chronic disability from occupational diseases in the Russian Federation in 2019 showed that there is a high level disability. Among occupational diseases in the Republic of Mordovia, the problem of mercury toxicity remains acute because of the industrial use of mercury or its compounds. The victims often suffer several mental and physical disorders simultaneously, which significantly complicates the process of rehabilitation and habilitation, and the socialization of patients exposed to the toxic effects of mercury and its compounds.

AIM: The aim was to determine the level of mental, neuromuscular, skeletal and movement-related (statodynamic) disorders arising from the toxic effects of mercury and its compounds in different age groups. Additionally, to study the relationship between the degree of loss of PАW because of occupational diseases, and the presence of complications due to concomitant diseases.

MATERIALS AND METHODS: The subjects of the study were patients aged 18 years and older who lost their PAW because of the toxic effects of mercury and its compounds, International Classification of Diseases, 10th revision (ICD-10) code: T56.1. A comprehensive study of patients who were newly or previously recognized as disabled was done by the Bureau of Medical and Social Expertise of the Republic of Mordovia. They assessed the degree of impairment of mental and statodynamic function for the period of 2015 to 2020. Data collection and processing, comparative analyses, expert assessment of the level of mental and statodynamic function disorders, and the status of the main and concomitant diseases and their complications was done.

RESULTS: For occupational diseases caused by the toxicity of mercury and its compounds, several assessments were done: the degree of loss of PAW, the need for medical, social and vocational rehabilitation, and classification of the patient as disabled as a result of occupational and general diseases in the presence of concomitant pathology. The percentage loss of PAW was determined: in 24.32% of cases. The percentage PAW loss and proportion of cases was 10% in 20.11% of cases, 20% in 13.41%, 30% in 12.34%, 40% in 1.28%, 50% in 3.85%, 60%, in 2.57%, 70% in 0.14%, and 80%, in 21.96%, respectively.

CONCLUSION: The toxic effect of mercury and its compounds caused disorders of mental functions. The minor-to-moderate and pronounced were most often detected, at 72.11%. The proportion of unaffected persons was 21.96%. Impairment of statodynamic function was detected in 2.63% of cases, and cardiovascular system function, 2.07%. There were sensory disorders in 0.71%, endocrine system and metabolic disorders in 0.14%, and blood and immune system abnormalities in 0.36%. The age categories were represented by two groups of persons: with persistent moderate and severe disorders of the body functions; persons from 45 to 59 years old inclusive; who had moderate, severe and significantly pronounced disorders, and the category of 60 year old patients.

Keywords

disability / mental disorders / mercury and its compounds / medical and social expertise / rehabilitation

References

[1] Dymochka MA, Krasnovskaya ES, Verigina NB. Figures of disability among the adult population of the Russian Federation over 2017–2019 (information analysis product). Medical-Social Problems of Disability. 2020;(2):7-26. (In Russ).

[2] Дымочка М.А., Красновская Е.С., Веригина Н.Б. Показатели инвалидности у взрослого населения Российской Федерации за период 2017–2019 гг. (информационно-аналитический материал) // Медико-социальные проблемы инвалидности. 2020. № 2. С. 7–26.

[3] Dmitriev VN, Andreeva NA, Urusova MA. Morbidity of the adult population of the Russian Federation by classes of diseases in dynamics for 2010-2018 / Morbidity of the adult population of the russian federation to diseases classes in dynamics over 2010–2018. Medical-Social Problems of Disability. 2020;(2):27–32. (In Russ).

[4] Дмитриев В.Н., Андреева Н.А., Урусова М.А. Заболеваемость взрослого населения Российской Федерации по классам болезней в динамике за 2010–2018 гг. // Медико-социальные проблемы инвалидности. 2020. № 2. С. 27–32.

[5] Order of the Ministry of Labor of Russian Federation of September 30, 2020 No 687n "Ob utverzhdenii kriteriev opredeleniya stepeni utraty professional’noj trudosposobnosti v rezul’tate neschastnyh sluchaev na proizvodstve i professional’nyh zabolevanij”. Available from: https://www.consultant.ru/document/cons_doc_LAW_371033 (In Russ).

[6] Приказ Минтруда России от 30.09.2020 № 687н «Об утверждении критериев определения степени утраты профессиональной трудоспособности в результате несчастных случаев на производстве и профессиональных заболеваний». Режим доступа: https://www.consultant.ru/document/cons_doc_LAW_371033

[7] The main indicators of primary disability of the adult population in the Russian Federation in 2019. Statistical collection. Moscow: ITU FB, 2020. 260 p. (In Russ).

[8] Основные показатели первичной инвалидности взрослого населения в Российской Федерации в 2019 году : статистический сборник. М.: ФБ МСЭ, 2020. 260 с.

[9] The main indicators of repeated disability of the adult population in the Russian Federation in 2019. Statistical collection. Moscow: ITU FB; 2020. 260 p. (In Russ).

[10] Основные показатели повторной инвалидности взрослого населения в Российской Федерации в 2019 году : статистический сборник. М.: ФБ МСЭ, 2020. 260 с.

[11] Decree of the Government of the Russian Federation of October 16, 2000 No 789 “Ob utverzhdenii Pravil ustanovleniya stepeni utraty professional’noi trudosposobnosti v rezul’tate neschastnykh sluchaev na proizvodstve i professional’nykh zabolevanii”. Available from: https://base.garant.ru/182595. (In Russ).

[12] Постановление Правительства РФ от 16 октября 2000 г. № 789 «Об утверждении Правил установления степени утраты профессиональной трудоспособности в результате несчастных случаев на производстве и профессиональных заболеваний». Режим доступа: https://base.garant.ru/182595

[13] Pomnikov VG, editor. Spravochnik po mediko-sotsial’noi ekspertize i reabilitatsii : in 2 vol. Saint Petersburg: Hippocrates; 2021. Vol. 1. 640 p. (In Russ).

[14] Справочник по медико-социальной экспертизе и реабилитации : в 2-х т. / под ред. В.Г. Помникова. 5-е изд., перераб. и доп. СПб.: Гиппократ, 2021. Т. 1. 640 с.

[15] Pomnikov VG, editor. Spravochnik po mediko-sotsial’noiekspertize i reabilitatsii : in 2 vol. Saint Petersburg: Hippocrates; 2021. Vol. 2. 528 p. (In Russ).

[16] Справочник по медико-социальной экспертизе и реабилитации : в 2-х т. / под ред. В.Г. Помникова. 5-е изд., перераб. и доп. СПб.: Гиппократ, 2021. Т. 2. 528 с.

[17] Pomnikov VG, Penina GO, editors. Sto let mediko-sotsial’noiekspertizy. Aktual’nye problemy i reabilitatsiya : cbornik trudov. Saint Petersburg: Aising; 2018. 288 p. (In Russ).

[18] Сто лет медико-социальной экспертизы. Актуальные проблемы и реабилитация : cборник трудов / под ред. В.Г. Помникова, Г.О. Пениной. СПб.: Айсинг, 2018. 288 с.

[19] Labunskiy D, Kiryukhina S, Podsevatkin V. Comparison of experimental cellular and molecular therapy in motor neuron disease. Eur J Neurol. 2019;26(1):829.

[20] Labunskiy D., Kiryukhina S., Podsevatkin V. Comparison of experimental cellular and molecular therapy in motor neuron disease // Eur J Neurol. 2019. Vol. 26, Suppl 1. P. 829.

[21] Labunskiy D, Kiryukhina S, Podsevatkin V. Hyperbaric oxygenation in treatment of tourette of disease in comparison with medication therapy and their influence of immunity parameters. Eur J Neurol. 2019;26(1):949.

[22] Labunskiy D., Kiryukhina S., Podsevatkin V. Hyperbaric oxygenation in treatment of tourette of disease in comparison with medication therapy and their influence of immunity parameters. Eur J Neurol. 2019. Vol. 26, Suppl 1. P. 949.

[23] Labunskiy D, Kiryukhina S, Kolmykova N. First scientific description of the hepatolenticular degeneration. Abstracts of the MDS Virtual Congress; September 2020. Р. 231. Available from: https://www.mdscongress.org/Congress-Branded/Congress- 2020-Files/MDSVirtualCongressBasicScienceAbstracts.pdf. Accessed: August 3, 2022.

[24] Labunskiy D., Kiryukhina S., Kolmykova N. First scientific description of the hepatolenticular degeneration // Abstracts of the MDS Virtual Congress; September 2020. Р. 231. Режим доступа: https://www.mdscongress.org/Congress-Branded/Congress-2020-Files/MDSVirtualCongressBasicScienceAbstracts.pdf. Accessed: August 3, 2022.

[25] Labunskiy D, Yurasova E, Kurgaev N, et al. Endocrine predicts of the formation of complex motor tics in tourette’s disease. Abstracts of the MDS Virtual Congress; September 2020. Р. 1456. Available from: https://www.mdscongress.org/Congress-Branded/Congress-2020- Files/MDSVirtualCongressBasicScienceAbstracts.pdf. Accessed: August 3, 2022.

[26] Labunskiy D., Yurasova E., Kurgaev N., et al. Endocrine predicts of the formation of complex motor tics in tourette’s disease // Abstracts of the MDS Virtual Congress; September 2020. Р. 1456. Режим доступа: https://www.mdscongress.org/Congress-Branded/Congress-2020-Files/MDSVirtualCongressBasicScienceAbstracts.pdf. Accessed: August 3, 2022.

[27] Kiryukhina SV, Gulina OV, Podsevatkin VG, et al. Analysis of disability due to organic mental disorders for 2019 in the Republic of Mordovia. Medical and Social Expert Evaluation and Rehabilitation. 2021;24(1):23–9. (In Russ). doi: 10.17816/MSER56386

[28] Кирюхина С.В., Гулина О.В., Подсеваткин В.Г., и др. Анализ инвалидности вследствие органических психических расстройств за 2019 год по Республике Мордовия // Медико-социальная экспертиза и реабилитация. 2021. Т. 24, №1. C. 23–29. doi: 10.17816/MSER56386

[29] Labunskiy D, Kiryukhina S, Podsevatkin V. Cytokines and brain specific antibodies in experimental cellular and molecular treatment of huntington’s diseases. Abstracts of the MDS Virtual Congress; September 2020. Р. 253. Available from: https://www.mdscongress.org/Congress-Branded/Congress-2020-Files/MDSVirtualCongressBasicScienceAbstracts.pdf. Accessed: August 3, 2022.

[30] Labunskiy D., Kiryukhina S., Podsevatkin V. Cytokines and brain specific antibodies in experimental cellular and molecular treatment of huntington’s diseases // Abstracts of the MDS Virtual Congress; September 2020. Р. 253. Режим доступа: https://www.mdscongress.org/Congress-Branded/Congress-2020-Files/MDSVirtualCongressBasicScienceAbstracts.pdf. Accessed: August 3, 2022.

[31] Gulina OV, Kiryukhina SV, Podsevatkin VG, et al. Statistical analysis of children with disabilities with obesity for 2018-2019 in the Republic of Mordovia. Medical and Social Expert Evaluation and Rehabilitation. 2020;23(3):18–23. (In Russ). doi: 10.17816/MSER51490

[32] Гулина О.В., Кирюхина С.В., Подсеваткин В.Г., и др. Статистический анализ детей-инвалидов с ожирением за 2018–2019 гг. по Республике Мордовия // Медико-социальная экспертиза и реабилитация. 2020. Т. 23, №3. C. 18–23. doi: 10.17816/MSER51490

RIGHTS & PERMISSIONS

Eco-Vector