Regional peculiarities of disability due to uterine cancer

Abstract

BACKGROUND: The federal project “Fight against oncological diseases for 2018–2024” has been launched in Russia within the framework of the national project “Healthcare.” There is significant regional variability in the level and severity of malignant neoplasms (MN), which determines the relevance of studying and monitoring the characteristics of health disorders due to MN in the regions. Disability, as the most important indicator of population health, makes the judgment of the effectiveness of treatment, rehabilitation, and preventive measures possible.

AIMS: To analyze the dynamics and structure of the disability of the female population due to uterine cancer in the Chechen Republic

MATERIALS AND METHODS: Units of observation included newly recognized disabled (NRD) and repeated recognized disabled (RRD) due to uterine cancer during the year. The object of the study included a combination of NRD and RRD due to uterine cancer in the Chechen Republic. The analysis was conducted by three age groups of the adult population (young, middle, and old). This epidemiological, retrospective, and evaluative study was conducted from 2014 to 2020 using documentary, data copying, statistical, and graphical research methods.

RESULTS: The age structure of disability due to uterine cancer revealed 218 (65.5%) elderly, 87 (26.1%) middle-aged, and 28 (8.4%) young females with disabilities. The dynamics by 2020 established that the contingent of young people with disabilities has not significantly changed, with decreased middle-aged and increased elderly females (p=0.0070). The third and second group of disabilities was more often established during the repeated (66.1%) and new (45.6%) examinations, respectively. Concurrently, the proportion of disabled people who were assigned to the first disability group was higher in the RRD cohort. Persistent dysfunctions of the blood system and immune system (100%) in disabled people were accompanied by various types of capacity limitations, with the predominance first degree of their severity. Moreover, a violation of the ability to work of the second degree was diagnosed with a large proportion in the young age segment of the disabled.

CONCLUSION: Within the framework of the project “Fight against oncological diseases for 2018–2024,” considering the regional features of the dynamics and structure of the disability of the female population is necessary due to uterine cancer in the Chechen Republic. The presented results of epidemiological and clinical-expert diagnostics should be used in the development of priority areas of anticancer medical and social activities for the prevention of disability (primary and secondary) due to oncogynecological diseases at the regional healthcare level.

Keywords

disability / uterine cancer / primary / repeated / structure / functional impairment / capacity limitations

References

[1] Kaprin AD, Starinsky VV, Shakhzadova AO. Malignant neoplasms in Russia in 2020 (morbidity and mortality). Moscow; 2021. 252 p. (In Russ).

[2] Каприн А.Д., Старинский В.В., Шахзадова А.О. Злокачественные новообразования в России в 2020 году (заболеваемость и смертность). Москва, 2021. 252 с.

[3] Bray F, Ferlay J, Soerjomataram I, et al. Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 cancers in 185 Countries. Ca Cancer J Clin. 2018;68(6):1394–1424. doi: 10.3322/caac.21492

[4] Bray F., Ferlay J., Soerjomataram I., et al. Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 cancers in 185 countries // Ca Cancer J Clin. 2018. Vol. 68, N 6. P. 1394–1424. doi: 10.3322/caac.21492

[5] Makimbetov EK, Salihar RI, Tumanbaev AM, et al. Epidemiology of cancer in the world. Modern Problems of Science and Education. 2020;(2):168. (In Russ).

[6] Макимбетов Э.К., Салихар Р.И., Туманбаев А.М., и др. Эпидемиология рака в мире // Современные проблемы науки и образования. 2020. № 2. С. 168.

[7] Kaprin AD, Ashrafyan LA, Stilidi IS. Oncogynecology: national guidelines. Moscow: GEOTAR-Media; 2019. 384 p. (In Russ). doi: 10.33029/9704-5329-2-ONR-2019-1-384

[8] Каприн А.Д., Ашрафян Л.А., Стилиди И.С. Онкогинекология: национальное руководство. Москва: ГЭОТАР-Медиа, 2019. 384 с. doi: 10.33029/9704-5329-2-ONR-2019-1-384

[9] Colombo N, Creutzberg C, Amant F, et al. ESMO-ESGO-ESTRO Consensus conference on endometrial cancer. Diagnosis, treatment and follow-up. Int J Gynecol Cancer. 2016;26(1):2–30. doi: 10.1093/annonc/mdv484

[10] Colombo N., Creutzberg C., Amant F., et al. ESMO-ESGO-ESTRO Consensus conference on endometrial cancer. Diagnosis, treatment and follow-up // Int J Gynecol Cancer. 2016. Vol. 26, N 1. P. 2–30. doi: 10.1093/annonc/mdv484

[11] Fan Z, Li H, Hu R, et al. Fertility-preserving treatment in young women with grade 1 presumed stage IA endometrial adenocarcinoma: a meta-analysis. Int J Gynecol Cancer. 2018;28(2):385–393. doi: 10.1097/IGC.0000000000001164

[12] Fan Z., Li H., Hu R., et al. Fertility-preserving treatment in young women with grade 1 presumed stage IA endometrial adenocarcinoma: a meta-analysis // Int J Gynecol Cancer. 2018. Vol. 28, N 2. Р. 385–393. doi: 10.1097/IGC.0000000000001164

[13] Dmitriev VN. Malignant neoplasms of the female reproductive system in the Belgorod region in comparison with all-Russian indicators: monograph. Belgorod: Epicenter; 2015. 212 p. (In Russ).

[14] Дмитриев В.Н. Злокачественные новообразования женской репродуктивной системы в Белгородской области в сопоставлении с общероссийскими показателями: монография. Белгород: Эпицентр, 2015. 212 с.

[15] Gordienko VP, Leont’eva SN, Korobkova TN. Cancer of the reproductive organs in women of the Far Eastern Federal District. Siberian Journal of Oncology. 2020;19(3):23–37. (In Russ). doi: 10.21294/1814-4861-2020-19-2-23-37

[16] Гордиенко В.П., Леонтьева С.Н., Коробкова Т.Н. Рак репродуктивных органов у женщин Дальневосточного федерального округа // Сибирский онкологический журнал. 2020. Т. 19, № 3. С. 23–37. doi: 10.21294/1814-4861-2020-19-2-23-37

[17] Puzin SN, Shurgaya MA, Dmitrieva NV. Epidemiology of adult disability in the Russian Federation. Epidemiology and Vaccination. 2019;18(5):14–23. (In Russ). doi: 10.31631/2073-3046-219-18-5-14-23

[18] Пузин С.Н., Шургая М.А., Дмитриева Н.В., и др. Эпидемиология инвалидности взрослого населения в Российской Федерации // Эпидемиология и вакцинопрофилактика. 2019. Т. 18, № 5. C. 14–23. doi: 10.31631/2073-3046-219-18-5-14-23

[19] National project “Health care”: federal project “Fight against oncological diseases”. Approved December 24, 2018 (implementation period 2019–2024). (In Russ). Available from: http://government.ru/. Accessed: 28.01.2022.

[20] Национальный проект «Здравоохранение»: федеральный проект «Борьба с онкологическими заболеваниями» (утв. 24 декабря 2018 г.; срок реализации 2019–2024 гг.). Режим доступа: http://government.ru/. Дата обращения: 28.01.2022.

[21] Emons G, Steiner E, Vordermark D, et al. Interdisciplinary diagnosis, therapy and follow-up of patients with endometrial cancer. Guideline (S3-Level, AWMF Registry Number 032/034-OL, April 2018) ― Part 2 with Recommendations on the therapy and follow-up of endometrial cancer, palliative care, psycho-oncological/ psychosocial care/rehabilitation/patient information and healthcare facilities. Geburtshilfe Frauenheilkd. 2018;78(11):1089–1109. doi: 10.1055/a-0715-2964

[22] Emons G., Steiner E., Vordermark D., et al. Interdisciplinary diagnosis, therapy and follow-up of patients with endometrial cancer. Guideline (S3-Level, AWMF Registry Number 032/034-OL, April 2018) – Part 2 with Recommendations on the therapy and follow-up of endometrial cancer, palliative care, psycho-oncological/psychosocial care/rehabilitation/patient information and healthcare facilities // Geburtshilfe Frauenheilkd. 2018. Vol. 78, N 11. P. 1089–1109. doi: 10.1055/a-0715-2964

[23] Nechushkina VM, Dengina NV, Kolomiets LA, et al. Practical recommendations for the treatment of uterine body cancer and uterine sarcomas. Malignant Tumors. 2018;8(3S2):190–203. (In Russ). doi: 10.18027/2224-5057-2017-7-3s2-168-180

[24] Нечушкина В.М., Деньгина Н.В., Коломиец Л.А., и др. Практические рекомендации по лечению рака тела матки и сарком матки // Злокачественные опухоли. 2018. Т. 8, № 3S2. С. 190–203. doi: 10.18027/2224-5057-2017-7-3s2-168-180

[25] Ogryzko EV, Ivanova MA, Golubev NA. Dynamics of “rough” and standardized indicators of morbidity and mortality of the population of Russia from malignant neoplasms for 2003–2016. Problems of Standardization in Healthcare. 2018(1-2):9–13. (In Russ). doi: 10.26347/1607-2502201801-02009-013

[26] Огрызко Е.В., Иванова М.А., Голубев Н.А., и др. Динамика «грубых» и стандартизированных показателей заболеваемости и смертности населения России от злокачественных новообразований за 2003–2016 годы // Проблемы стандартизации в здравоохранении. 2018. № 1-2. С. 9–13. doi: 10.26347/1607-2502201801-02009-013

[27] Shurgaya MA. Malignant neoplasms: age-related features of the epidemiology of primary disability in the Russian Federation. Russian Journal of Oncology. 2016;21(6):319–324. (In Russ). doi: 10.18821/1028-9984-2016-21-6-319-324

[28] Шургая М.А. Злокачественные новообразования: возрастные особенности эпидемиологии первичной инвалидности в Российской Федерации // Российский онкологический журнал. 2016. Т. 21, № 6. С. 319–324. doi: 10.18821/1028-9984-2016-21-6-319-324

[29] Van den Bosch T, Coosemans A, Morina M, et al. Screening for uterine tumours. Best Pract Res Clin Obstet Gynaecol. 2012;26(2):257–266. doi: 10.1016/j.bpobgyn.2011.08.002

[30] Van den Bosch T., Coosemans A., Morina M., et al. Screening for uterine tumours // Best Pract Res Clin Obstet Gynaecol. 2012. Vol. 26, N 2. P. 257–266. doi: 10.1016/j.bpobgyn.2011.08.002

RIGHTS & PERMISSIONS

Eco-Vector