Epidemiology, course and predictors of long-term COVID infection (long COVID): A review

Anna E. Tsygankova , Andrey N. Gerasimov , Valerii A. Malov , Olga V. Darvina , Elena V. Volchkova , Vladimir P. Chulanov

Epidemiology and Infectious Diseases ›› 2024, Vol. 29 ›› Issue (1) : 64 -73.

PDF (754KB)
Epidemiology and Infectious Diseases ›› 2024, Vol. 29 ›› Issue (1) : 64 -73. DOI: 10.17816/EID610995
Reviews
review-article

Epidemiology, course and predictors of long-term COVID infection (long COVID): A review

Author information +
History +
PDF (754KB)

Abstract

The COVID-19 pandemic has posed a serious challenge to the healthcare system in the 21st century. At present, over 771 million cases have been reported worldwide. Apart from the acute symptoms, many patients experience long-term consequences of the infection, which greatly affect their quality of life. The collection of these long-term effects is called “long COVID.” Therefore, the consequences of COVID-19 must be studied to develop effective strategies for combating them. This review aimed to provide an overview of the history of long COVID and discuss the characteristics of contemporary terminology. This review also presents data on the prevalence of long COVID, primary symptoms, and risk factors and explores potential biomarkers, prognosis, and prospects for subsequent clinical trials.

Keywords

postacute COVID-19 syndrome / long COVID-19 / COVID-19 complications

Cite this article

Download citation ▾
Anna E. Tsygankova, Andrey N. Gerasimov, Valerii A. Malov, Olga V. Darvina, Elena V. Volchkova, Vladimir P. Chulanov. Epidemiology, course and predictors of long-term COVID infection (long COVID): A review. Epidemiology and Infectious Diseases, 2024, 29(1): 64-73 DOI:10.17816/EID610995

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Mathieu E, Ritchie H, Rodés-Guirao L, et al. Coronavirus Pandemic (COVID-19). Our World in Data. 2020. Available at: https://ourworldindata.org/coronavirus#coronavirus-country-profiles

[2]

Еженедельный бюллетень по гриппу [интернет] [дата обращения: 16.10.2023]. Режим доступа: https://www.influenza.spb.ru/system/epidemic_situation/laboratory_diagnostics/.

[3]

Ezhenedel’nyi byulleten’ po grippu [Internet] [cited 2023 Oct 16]. (In Russ). Available at: https://www.influenza.spb.ru/system/epidemic_situation/laboratory_diagnostics/.

[4]

Yong E. COVID-19 Can last for several months // The Atlantic [Internet]. Режим доступа: https://www.theatlantic.com/health/archive/2020/06/covid-19-coronavirus-longterm-symptoms-months/612679/.

[5]

Yong E. COVID-19 Can Last for Several Months. The Atlantic [Internet]. Available at: https://www.theatlantic.com/health/archive/2020/06/covid-19-coronavirus-longterm-symptoms-months/612679/.

[6]

Soriano J.B., Murthy S., Marshall J.C., Relan P., Diaz J.V.; WHO Clinical Case Definition Working Group on Post-COVID-19 Condition. A clinical case definition of post-COVID-19 condition by a Delphi consensus // The Lancet. Infectious Diseases. 2022. Vol. 22, N 4. P. e102–e107. doi: 10.1016/S1473-3099(21)00703-9

[7]

Soriano JB, Murthy S, Marshall JC, Relan P, Diaz JV; WHO Clinical Case Definition Working Group on Post-COVID-19 Condition. A clinical case definition of post-COVID-19 condition by a Delphi consensus. The Lancet. Infectious Diseases. 2022;22(4):e102-e107. doi: 10.1016/S1473-3099(21)00703-9

[8]

Callard F., Perego E. How and why patients made Long Covid // Social Science & Medicine. 2021. Vol. 268. C. 113426. doi: 10.1016/j.socscimed.2020.113426

[9]

Callard F, Perego E. How and why patients made Long Covid. Social Science & Medicine. 2021;268:113426. doi: 10.1016/j.socscimed.2020.113426

[10]

Michelen M., Manoharan L., Elkheir N., et al. Characterising long COVID: a living systematic review // BMJ Global Health. 2021. Vol. 6, N 9. C. e005427. doi: 10.1136/bmjgh-2021-005427

[11]

Michelen M, Manoharan L, Elkheir N, et al. Characterising long COVID: a living systematic review. BMJ Global Health. 2021;6(9):e005427. doi: 10.1136/bmjgh-2021-005427

[12]

Behnood S.A., Shafran R., Bennett S.D., et al. Persistent symptoms following SARS-CoV-2 infection amongst children and young people: A meta-analysis of controlled and uncontrolled studies // Journal of Infection. 2022. Vol. 84, N 2. P. 158–170. doi: 10.1016/j.jinf.2021.11.011

[13]

Behnood SA, Shafran R, Bennett SD, et al. Persistent symptoms following SARS-CoV-2 infection amongst children and young people: A meta-analysis of controlled and uncontrolled studies. Journal of Infection. 2022;84(2):158–170. doi: 10.1016/j.jinf.2021.11.011

[14]

Fernández-de-Las-Peñas C., Palacios-Ceña D., Gómez-Mayordomo V., Cuadrado M.L., Florencio L.L. Defining Post-COVID Symptoms (Post-Acute COVID, Long COVID, Persistent Post-COVID): An Integrative Classification // International Journal of Environmental Research and Public Health. 2021. Vol. 18, N 5. P. 2621. doi: 10.3390/ijerph18052621

[15]

Fernández-de-Las-Peñas C, Palacios-Ceña D, Gómez-Mayordomo V, Cuadrado ML, Florencio LL. Defining Post-COVID Symptoms (Post-Acute COVID, Long COVID, Persistent Post-COVID): An Integrative Classification. International Journal of Environmental Research and Public Health. 2021;18(5):2621. doi: 10.3390/ijerph18052621

[16]

Fernández-de-Las-Peñas C. Long COVID: current definition // Infection. 2022. Vol. 50, N 1. P. 285–286. doi: 10.1007/s15010-021-01696-5

[17]

Fernández-de-Las-Peñas C. Long COVID: current definition. Infection. 2022;50(1):285–286. doi: 10.1007/s15010-021-01696-5

[18]

Boscolo-Rizzo P., Borsetto D., Fabbris C., et al. Evolution of Altered Sense of Smell or Taste in Patients With Mildly Symptomatic COVID-19 // JAMA Otolaryngology — Head & Neck Surgery. 2020. Vol. 146, N 8. P. 729–732. doi: 10.1001/jamaoto.2020.1379

[19]

Boscolo-Rizzo P, Borsetto D, Fabbris C, et al. Evolution of altered sense of smell or taste in patients with mildly symptomatic COVID-19. JAMA Otolaryngology — Head & Neck Surgery. 2020;146(8):729−732. doi: 10.1001/jamaoto.2020.1379

[20]

Lopez-Leon S., Wegman-Ostrosky T., Perelman C., et al. More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis // medRxiv. 2021. doi: 10.1101/2021.01.27.21250617

[21]

Lopez-Leon S, Wegman-Ostrosky T, Perelman C, et al. More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis. medRxiv. 2021. doi: 10.1101/2021.01.27.21250617

[22]

Blomberg B., Mohn K.G., Brokstad K.A., et al. Long COVID in a prospective cohort of home-isolated patients // Nature Medicine. 2021. Vol. 27, N 9. P. 1607–1613. doi: 10.1038/s41591-021-01433-3

[23]

Blomberg B, Mohn KG, Brokstad KA, et al. Long COVID in a prospective cohort of home-isolated patients. Nature Medicine. 2021;27(9):1607-1613. doi: 10.1038/s41591-021-01433-3

[24]

Mullard A. Long COVID’s long R&D agenda // Nature Reviews. Drug Discovery. 2021. Vol. 20, N 5. C. 329–331. doi: 10.1038/d41573-021-00069-9

[25]

Mullard A. Long COVID’s long R&D agenda. Nature Reviews. Drug Discovery. 2021;20(5):329–331. doi: 10.1038/d41573-021-00069-9

[26]

Dennis A., Wamil M., Alberts J., et al. Multiorgan impairment in low-risk individuals with post-COVID-19 syndrome: a prospective, community-based study // BMJ open. 2021. Vol. 11, N 3. P. e048391. doi: 10.1136/bmjopen-2020-048391

[27]

Dennis A, Wamil M, Alberts J, et al. Multiorgan impairment in low-risk individuals with post-COVID-19 syndrome: a prospective, community-based study. BMJ Open. 2021;11(3):e048391. doi: 10.1136/bmjopen-2020-048391

[28]

Groff D., Sun A., Ssentongo A.E., et al. Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection: A Systematic Review // JAMA network open. 2021. Vol. 4, N 10. P. e2128568. doi: 10.1001/jamanetworkopen.2021.28568

[29]

Groff D, Sun A, Ssentongo AE, et al. Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection: A Systematic Review. JAMA network open. 2021;4(10):e2128568. doi: 10.1001/jamanetworkopen.2021.28568

[30]

Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK — Office for National Statistics [Internet]. Режим доступа: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/2february2023.

[31]

Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK — Office for National Statistics [Internet]. Available at: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/2february2023.

[32]

Freedberg D.E., Chang L. Gastrointestinal symptoms in COVID-19: the long and the short of it // Current Opinion in Gastroenterology. 2022. Vol. 38, N 6. P. 555–561. doi: 10.1097/MOG.0000000000000876

[33]

Freedberg DE, Chang L. Gastrointestinal symptoms in COVID-19: the long and the short of it. Current Opinion in Gastroenterology. 2022;38(6):555–561. doi: 10.1097/MOG.0000000000000876

[34]

Pinzon R.T., Wijaya V.O., Jody A.A., Nunsio P.N., Buana R.B. Persistent neurological manifestations in long COVID-19 syndrome: A systematic review and meta-analysis // Journal of Infection and Public Health. 2022. Vol. 15, N 8. P. 856–869. doi: 10.1016/j.jiph.2022.06.013

[35]

Pinzon RT, Wijaya VO, Jody AA, Nunsio PN, Buana RB. Persistent neurological manifestations in long COVID-19 syndrome: A systematic review and meta-analysis. Journal of Infection and Public Health. 2022;15(8):856–869. doi: 10.1016/j.jiph.2022.06.013

[36]

Bouayed J., Bohn T. Adapted sickness behavior — Why it is not enough to limit the COVID-19 spread? // Brain, Behavior, and Immunity. 2021. Vol. 93. P. 4–5. doi: 10.1016/j.bbi.2020.12.028

[37]

Bouayed J, Bohn T. Adapted sickness behavior — Why it is not enough to limit the COVID-19 spread? Brain, Behavior, and Immunity. 2021;93:4–5. doi: 10.1016/j.bbi.2020.12.028

[38]

Daitch V., Yelin D., Awwad M., et al. Characteristics of long-COVID among older adults: a cross-sectional study // International journal of infectious diseases. 2022. Vol. 125. P. 287–293. doi: 10.1016/j.ijid.2022.09.035

[39]

Daitch V, Yelin D, Awwad M, et al. Characteristics of long-COVID among older adults: a cross-sectional study. International journal of infectious diseases. 2022;125:287–293. doi: 10.1016/j.ijid.2022.09.035

[40]

Lu Y., Li X., Geng D., et al. Cerebral Micro-Structural Changes in COVID-19 Patients — An MRI-based 3-month Follow-up Study // EClinicalMedicine. 2020. Vol. 25. P. 100484. doi: 10.1016/j.eclinm.2020.100484

[41]

Lu Y, Li X, Geng D, et al. Cerebral Micro-Structural Changes in COVID-19 Patients — An MRI-based 3-month Follow-up Study. EClinicalMedicine. 2020;25:100484. doi: 10.1016/j.eclinm.2020.100484

[42]

Miyazato Y., Morioka S., Tsuzuki S., et al. Prolonged and Late-Onset Symptoms of Coronavirus Disease 2019 // Open Forum Infectious Diseases. 2020. Vol. 7, N 11. P. ofaa507. doi: 10.1093/ofid/ofaa507

[43]

Miyazato Y, Morioka S, Tsuzuki S, et al. Prolonged and Late-Onset Symptoms of Coronavirus Disease 2019. Open Forum Infectious Diseases. 2020;7(11):ofaa507. doi: 10.1093/ofid/ofaa507

[44]

Townsend L., Dyer A.H., Jones K., et al. Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection // PloS One. 2020. Vol. 15, N 11. P. e0240784. doi: 10.1371/journal.pone.0240784

[45]

Townsend L, Dyer AH, Jones K, et al. Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection. PLoS One. 2020;15(11):e0240784. doi: 10.1371/journal.pone.0240784

[46]

Van den Borst B., Peters J.B., Brink M., et al. Comprehensive Health Assessment 3 Months After Recovery From Acute Coronavirus Disease 2019 (COVID-19) // Clinical Infectious Diseases. 2021. Vol. 73, N 5. P. e1089–e1098. doi: 10.1093/cid/ciaa1750

[47]

Van den Borst B, Peters JB, Brink M, et al. Comprehensive Health Assessment 3 Months After Recovery From Acute Coronavirus Disease 2019 (COVID-19). Clinical Infectious Diseases. 2021;73(5):e1089–e1098. doi: 10.1093/cid/ciaa1750

[48]

Poyraz B.Ç., Poyraz C.A., Olgun Y., et al. Psychiatric morbidity and protracted symptoms after COVID-19 // Psychiatry Research. 2021. Vol. 295. P. 113604. doi: 10.1016/j.psychres.2020.113604

[49]

Poyraz BÇ, Poyraz CA, Olgun Y, et al. Psychiatric morbidity and protracted symptoms after COVID-19. Psychiatry research. 2021;295: 113604. doi: 10.1016/j.psychres.2020.113604

[50]

Taboada M., Cariñena A., Moreno E., et al. Post-COVID-19 functional status six-months after hospitalization // The Journal of Infection. 2021. Vol. 82, N 4. P. e31–e33. doi: 10.1016/j.jinf.2020.12.022

[51]

Taboada M., Cariñena A., Moreno E., et al. Post-COVID-19 functional status six-months after hospitalization // The Journal of Infection. 2021. Vol. 82, N 4. P. e31–e33. doi: 10.1016/j.jinf.2020.12.022

[52]

Raman B., Cassar M.P., Tunnicliffe E.M., et al. Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge // EClinicalMedicine. 2021. Vol. 31. P. 100683. doi: 10.1016/j.eclinm.2020.100683

[53]

Raman B., Cassar M.P., Tunnicliffe E.M., et al. Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge // EClinicalMedicine. 2021. Vol. 31. P. 100683. doi: 10.1016/j.eclinm.2020.100683

[54]

Halpin S.J., McIvor C., Whyatt G., et al. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation // Journal of Medical Virology. 2021. Vol. 93, N 2. P. 1013–1022. doi: 10.1002/jmv.26368

[55]

Halpin S.J., McIvor C., Whyatt G., et al. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation // Journal of Medical Virology. 2021. Vol. 93, N 2. P. 1013–1022. doi: 10.1002/jmv.26368

[56]

Whitaker M., Elliott J., Chadeau-Hyam M., et al. Persistent COVID-19 symptoms in a community study of 606,434 people in England // Nature Communications. 2022. Vol. 13, N 1. P. 1957. doi: 10.1038/s41467-022-29521-z

[57]

Whitaker M., Elliott J., Chadeau-Hyam M., et al. Persistent COVID-19 symptoms in a community study of 606,434 people in England // Nature Communications. 2022. Vol. 13, N 1. P. 1957. doi: 10.1038/s41467-022-29521-z

[58]

Ganesh R., Grach S.L., Ghosh A.K., et al. The Female-Predominant Persistent Immune Dysregulation of the Post-COVID Syndrome // Mayo Clinic Proceedings. 2022. Vol. 97, N 3. C. 454–464. doi: 10.1016/j.mayocp.2021.11.033

[59]

Ganesh R., Grach S.L., Ghosh A.K., et al. The Female-Predominant Persistent Immune Dysregulation of the Post-COVID Syndrome // Mayo Clinic Proceedings. 2022. Vol. 97, N 3. C. 454–464. doi: 10.1016/j.mayocp.2021.11.033

[60]

Antonelli M., Pujol J.C., Spector T.D., Ourselin S., Steves C.J. Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2 // The Lancet. 2022. Vol. 399, N 10343. P. 2263–2264. doi: 10.1016/S0140-6736(22)00941-2

[61]

Antonelli M., Pujol J.C., Spector T.D., Ourselin S., Steves C.J. Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2 // The Lancet. 2022. Vol. 399, N 10343. P. 2263–2264. doi: 10.1016/S0140-6736(22)00941-2

[62]

Klein J., Wood J., Jaycox J., et al. Distinguishing features of Long COVID identified through immune profiling // medRxiv. 2022. doi: 10.1101/2022.08.09.22278592

[63]

Klein J, Wood J, Jaycox J, et al. Distinguishing features of Long COVID identified through immune profiling. Preprint. medRxiv. 2022. doi: 10.1101/2022.08.09.22278592

[64]

Su Y., Yuan D., Chen D.G., et al. Multiple early factors anticipate post-acute COVID-19 sequelae // Cell. 2022. Vol. 185, N 5. P. 881–895.e20. doi: 10.1016/j.cell.2022.01.014

[65]

Su Y, Yuan D, Chen DG, et al. Multiple early factors anticipate post-acute COVID-19 sequelae. Cell. 2022;185(5):881–895.e20. doi: 10.1016/j.cell.2022.01.014

[66]

Lai Y.-J., Liu S.-H., Manachevakul S., et al. Biomarkers in long COVID-19: A systematic review // Frontiers in Medicine. 2023. Vol. 10. P. 1085988. doi: 10.3389/fmed.2023.1085988

[67]

Lai Y-J, Liu S-H, Manachevakul S, et al. Biomarkers in long COVID-19: A systematic review. Frontiers in Medicine. 2023; 10:1085988. doi: 10.3389/fmed.2023.1085988

[68]

Peluso M.J., Lu S., Tang A.F., et al. Markers of Immune Activation and Inflammation in Individuals With Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection // The Journal of Infectious Diseases. 2021. Vol. 224, N 11. P. 1839–1848. doi: 10.1093/infdis/jiab490

[69]

Peluso MJ, Lu S, Tang AF, et al. Markers of Immune Activation and Inflammation in Individuals With Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection. The Journal of Infectious Diseases. 2021;224(11):1839–1848. doi: 10.1093/infdis/jiab490

[70]

Polak S.B., Van Gool I.C., Cohen D., Von der Thüsen J.H., Van Paassen J. A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression // Modern Pathology. 2020. Vol. 33, N 11. P. 2128–2138. doi: 10.1038/s41379-020-0603-3

[71]

Polak SB, Van Gool IC, Cohen D, Von der Thüsen JH, Van Paassen J. A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression. Modern Pathology. 2020;33(11):2128–2138. doi: 10.1038/s41379-020-0603-3

[72]

Colarusso C., Maglio A., Terlizzi M., et al. Post-COVID-19 Patients Who Develop Lung Fibrotic-like Changes Have Lower Circulating Levels of IFN-β but Higher Levels of IL-1α and TGF-β // Biomedicines. 2021. Vol. 9, N 12. P. 1931. doi: 10.3390/biomedicines9121931

[73]

Colarusso C, Maglio A, Terlizzi M, et al. Post-COVID-19 Patients Who Develop Lung Fibrotic-like Changes Have Lower Circulating Levels of IFN-β but Higher Levels of IL-1α and TGF-β. Biomedicines. 2021;9(12):1931. doi: 10.3390/biomedicines9121931

[74]

Huang X., Xiu H., Zhang S., Zhang G. The Role of Macrophages in the Pathogenesis of ALI/ARDS // Mediators of Inflammation. 2018. Vol. 2018. P. 1264913. doi: 10.1155/2018/1264913

[75]

Huang X, Xiu H, Zhang S, Zhang G. The Role of Macrophages in the Pathogenesis of ALI/ARDS. Mediators of Inflammation. 2018;2018:1264913. doi: 10.1155/2018/1264913

[76]

Zhou X., Yang D., Kong X., et al. Case Report: Pirfenidone in the Treatment of Post-COVID-19 Pulmonary Fibrosis // Frontiers in Medicine. 2022. Vol. 9. P. 925703. doi: 10.3389/fmed.2022.925703

[77]

Zhou X, Yang D, Kong X, et al. Case Report: Pirfenidone in the Treatment of Post-COVID-19 Pulmonary Fibrosis. Frontiers in Medicine. 2022;9:925703. doi: 10.3389/fmed.2022.925703

[78]

Menzella F., Fontana M., Salvarani C., et al. Efficacy of tocilizumab in patients with COVID-19 ARDS undergoing noninvasive ventilation // Critical Care. 2020. Vol. 24, N 1. P. 589. doi: 10.1186/s13054-020-03306-6

[79]

Menzella F, Fontana M, Salvarani C, et al. Efficacy of tocilizumab in patients with COVID-19 ARDS undergoing noninvasive ventilation. Critical Care. 2020;24(1):589. doi: 10.1186/s13054-020-03306-6

[80]

Huang L., Li X., Gu X., et al. Health outcomes in people 2 years after surviving hospitalisation with COVID-19: a longitudinal cohort study // The Lancet Respiratory Medicine. 2022. Vol. 10, N 9. P. 863–876. doi: 10.1016/S2213-2600(22)00126-6

[81]

Huang L, Li X, Gu X, et al. Health outcomes in people 2 years after surviving hospitalisation with COVID-19: a longitudinal cohort study. The Lancet Respiratory Medicine. 2022;10(9):863–876. doi: 10.1016/S2213-2600(22)00126-6

[82]

Diem L., Schwarzwald A., Friedli C., et al. Multidimensional phenotyping of the post-COVID-19 syndrome: A Swiss survey study // CNS neuroscience & therapeutics. 2022. Vol. 28, N 12. P. 1953–1963. doi: 10.1111/cns.13938

[83]

Diem L, Schwarzwald A, Friedli C, et al. Multidimensional phenotyping of the post-COVID-19 syndrome: a Swiss survey study. CNS neuroscience & therapeutics. 2022;28(12):1953−1963. doi: 10.1111/cns.13938

[84]

Taquet M., Sillett R., Zhu L., et al. Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients // The Lancet. Psychiatry. 2022. Vol. 9, N 10. P. 815–827. doi: 10.1016/S2215-0366(22)00260-7

[85]

Taquet M, Sillett R, Zhu L, et al. Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients. The Lancet. Psychiatry. 2022;9(10):815−827. doi: 10.1016/S2215-0366(22)00260-7

[86]

Lee J.H., Yim J.-J., Park J. Pulmonary function and chest computed tomography abnormalities 6-12 months after recovery from COVID-19: a systematic review and meta-analysis // Respiratory Research. 2022. Vol. 23, N 1. P. 233. doi: 10.1186/s12931-022-02163-x

[87]

Lee JH, Yim J-J, Park J. Pulmonary function and chest computed tomography abnormalities 6-12 months after recovery from COVID-19: a systematic review and meta-analysis. Respiratory Research. 2022;23(1):233. doi: 10.1186/s12931-022-02163-x

[88]

Antonelli M., Pujol J.C., Spector T.D., Ourselin S., Steves C.J. Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2 // The Lancet. 2022. Vol. 399, N 10343. P. 2263–2264. doi: 10.1016/S0140-6736(22)00941-2

[89]

Antonelli M, Pujol JC, Spector TD, Ourselin S, Steves CJ. Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2. The Lancet. 2022;399(10343):2263–2264. doi: 10.1016/S0140-6736(22)00941-2

RIGHTS & PERMISSIONS

Eco-vector

AI Summary AI Mindmap
PDF (754KB)

97

Accesses

0

Citation

Detail

Sections
Recommended

AI思维导图

/