Trichinosis: outbreak description and brief literature review

Abstract

Presented here is a description of trichinosis outbreak associated with bear meat consumption in the form of basturma and chips. The clinical, epidemiological, and laboratory characteristics of the disease course in observed three patients are given. In addition, a review of modern literature on the problem of trichinosis is presented, including issues of etiology, epidemiology, developmental cycle of trichinella, and features of disease clinical course, diagnosis, and treatment. Criteria to be looked at when trichinosis is suspected are also discussed.

Keywords

trichinellosis / human trichinellosis / foodborne zoonoses / outbreak / case report / literature review

References

[1] Tolokonnikov VP, Mukhtarova GM. Environmental and pathogenetic bases of functioning of parasitic system formed by trichinella (Trichinella Railliet, 1895). South of Russia: ecology, development. 2015;10(3):85–91. (In Russ). doi: 10.18470/1992-1098-2015-3-85-91

[2] Толоконников В.П., Мухтарова Г.М. Экологические и патогенетические основы функционирования паразитарной системы, формируемой трихинеллой (Trichinella Railliet, 1895) // Юг России: экология, развитие. 2015. Т. 10, № 3. С. 85–91. doi: 10.18470/1992-1098-2015-3-85-91

[3] Tokmalaev AK, Kozevnikova GM. Clinical parasitology: protozoa and helminthiasis. Leadership for doctors. Second edition. Moscow: MIA; 2017. (In Russ).

[4] Токмалаев А.К., Кожевникова Г.М. Клиническая паразитология: протозоозы и гельминтозы: руководство для врачей. Изд. 2-е, доп. Москва: МИА, 2017.

[5] Bruschi F, Murrell KD. New aspects of human trichinellosis: the impact of new Trichinella species. Postgrad Med J. 2002;78(915):15–22. doi: 10.1136/pmj.78.915.15

[6] Bruschi F., Murrell K.D. New aspects of human trichinellosis: the impact of new Trichinella species // Postgraduate Medical Journal. 2002. Vol. 78, N 915. P. 15–22. doi: 10.1136/pmj.78.915.15

[7] Diaz J, Warren RJ, Oster M. The disease ecology, epidemiology, clinical manifestations, and management of trichinellosis linked to consumption of wild animal meat. Wilderness Environ Med. 2020;31(2):235–244. doi: 10.1016/j.wem.2019.12.003

[8] Diaz J., Warren R.J., Oster M. The disease ecology, epidemiology, clinical manifestations, and management of trichinellosis linked to consumption of wild animal meat // Wilderness & Environmental Medicine. 2020. Vol. 31, N 2. P. 235–244. doi: 10.1016/j.wem.2019.12.003

[9] Tsygankova ZI. An outbreak of trichinosis in the Kaliningrad region. Medical Parasitology and parasitic diseases. 2002;(4):51–52. (In Russ).

[10] Цыганкова З.И. Вспышка трихинеллеза в Калининградской области // Медицинская паразитология и паразитарные болезни. 2002. № 4. C. 51–52.

[11] Santos Durán-Ortiz J, García-de la Torre I, Orozco-Barocio G, et al. Trichinosis with severe myopathic involvement mimicking polymyositis. Report of a family outbreak. J Rheumatol. 1992;19(2):310–312.

[12] Santos Durán-Ortiz J., García-de la Torre I., Orozco-Barocio G., et al. Trichinosis with severe myopathic involvement mimicking polymyositis. Report of a family outbreak // The Journal of Rheumatology. 1992. Vol. 19, N 2. P. 310–312.

[13] Dubey ML, Khurana S, Singhan L, et al. Atypical trichinellosis without eosinophilia associated with osteomyelitis. Tropical Doctor. 2011;41(4):244–246. doi: 10.1258/td.2011.110106

[14] Dubey M.L., Khurana S., Singhan L., et al. Atypical trichinellosis without eosinophilia associated with osteomyelitis // Tropical Doctor. 2011. Vol. 41, N 4. P. 244–246. doi: 10.1258/td.2011.110106

[15] Bruschi F, Brunetti E, Pozio E. Neurotrichinellosis. Handbook Clin Neurol. 2013;114:243–249. doi: 10.1016/B978-0-444-53490-3.00019-4

[16] Bruschi F., Brunetti E., Pozio E. Neurotrichinellosis // Handbook of Clinical Neurologe. 2013. Vol. 114. P. 243–249. doi: 10.1016/B978-0-444-53490-3.00019-4

[17] Murrell KD, Pozio E. Trichinellosis: the zoonosis that won’t go quietly. Int J Parasitolog. 2000;30(12-13):1339–1349. doi: 10.1016/s0020-7519(00)00132-6

[18] Murrell K.D., Pozio E. Trichinellosis: the zoonosis that won’t go quietly // International Journal for Parasitology. 2000. Vol. 30, N 12-13. P. 1339–1349. doi: 10.1016/s0020-7519(00)00132-6

[19] Murrell KD, Lichtenfels RJ, Zarlenga DS, Pozio E. The systematics of the genus trichinella with a key to the species. Veterinar Parasitolog. 2000;93(3-4):293–307. doi: 10.1016/s0304-4017(00)00347-2

[20] Murrell K.D., Lichtenfels R.J., Zarlenga D.S., Pozio E. The systematics of the genus trichinella with a key to the species // Veterinary Parasitology. 2000. Vol. 93, N 3-4. P. 293–307. doi: 10.1016/s0304-4017(00)00347-2

[21] Kriuchkova EN, Abalikhin BG, Sokolov EA. The current situation of trichinellosis in the Central Non-Chernozem region of the Russian Federation. Veterinarnyi vrach. 2019;(5):28–32. (In Russ). doi: 10.33632/1998-698X.2019-5-28-32

[22] Крючкова Е.Н., Абалихин Б.Г., Соколов Е.А. Современная ситуация по трихинеллезу в Центральном Нечерноземье Российской Федерации // Ветеринарный врач. 2019. N 5. С. 28–32.

[23] Ancelle T, Dupouy-Camet J, Desenclos JC, et al. A multifocal outbreak of trichinellosis linked to horse meat imported from North America to France in 1993. Am J Tropical Med Hygiene. 1998;59(4):615–619. doi: 10.4269/ajtmh.1998.59.615

[24] Ancelle T., Dupouy-Camet J., Desenclos J.C., et al. A multifocal outbreak of trichinellosis linked to horse meat imported from North America to France in 1993 // American Journal of Tropical Medicine and Hygiene. 1998. Vol. 59, N 4. P. 615–619. doi: 10.4269/ajtmh.1998.59.615

[25] Murrell KD, Djordjevic M, Cuperlovic K, et al. Epidemiology of Trichinella infection in the horse: the risk from animal product feeding practices. Veterinary Parasitology. 2004;123(3-4):223–233. doi: 10.1016/j.vetpar.2004.06.008

[26] Murrell K.D., Djordjevic M., Cuperlovic K., et al. Epidemiology of Trichinella infection in the horse: the risk from animal product feeding practices // Veterinary Parasitology. 2004. Vol. 123, N 3-4. P. 223–233. doi: 10.1016/j.vetpar.2004.06.008

[27] Liciardi M, Marucci G, Addis G, et al. Trichinella britovi and Trichinella spiralis mixed infection in a horse from Poland. Veterinary Parasitology. 2009;161(3-4):345–348. doi: 10.1016/j.vetpar.2009.01.013

[28] Liciardi M., Marucci G., Addis G., et al. Trichinella britovi and Trichinella spiralis mixed infection in a horse from Poland // Veterinary Parasitology. 2009. Vol. 161, N 3-4. P. 345–348. doi: 10.1016/j.vetpar.2009.01.013

[29] Bourée P, Bouvier JB, Passeron J, et al. Outbreak of trichinosis near Paris. Br Med J. 1979;1(6170):1047–1049. doi: 10.1136/bmj.1.6170.1047

[30] Bourée P., Bouvier J.B., Passeron J., et al. Outbreak of trichinosis near Paris // British Medical Journal. 1979. Vol. 1, N 6170. P. 1047–1049. doi: 10.1136/bmj.1.6170.1047

[31] Ffrench GE Trichinosis [letter]. Br Med J. 1979;1(6174):1355. doi: 10.1136/bmj.1.6174.1355-a

[32] Ffrench G.E. Trichinosis [letter] // Br Med J. 1979. Vol. 1, N 6174. P. 1355. doi: 10.1136/bmj.1.6174.1355-a

[33] Tokmalaev AK. Trichinellosis. In: Yushchuk ND, editors. Infectious diseases: national leadership. Second edition. Moscow: GEOTAR-Media; 2009. Р. 1078–1085. (In Russ).

[34] Токмалаев А.К. Трихинеллез // Инфекционные болезни: национальное руководство / под ред. Н.Д. Ющук, Ю.Я. Венгеров. Изд 2-е, перераб. и доп. Москва: ГЭОТАР-Медиа, 2018. С. 1078–1085.

[35] Kaewpitoon N, Kaewpitoon SJ, Pengsaa P. Food-borne parasitic zoonosis: Distribution of trichinosis in Thailand. World J Gastroenterol. 2008;14(22):3471–3475. doi: 10.3748/wjg.14.3471

[36] Kaewpitoon N., Kaewpitoon S.J., Pengsaa P. Food-borne parasitic zoonosis: Distribution of trichinosis in Thailand // World Journal of Gastroenterology. 2008. Vol. 14, N 22. P. 3471–3475. doi: 10.3748/wjg.14.3471

[37] Turk M, Kaptan F, Turker N, et al. Clinical and laboratory aspects of a trichinellosis outbreak in Izmir, Turkey. Parasite. 2006;13(1):65–70. doi: 10.1051/parasite/2006131065

[38] Turk M., Kaptan F., Turker N., et al. Clinical and laboratory aspects of a trichinellosis outbreak in Izmir, Turkey // Parasite. 2006. Vol. 13, N 1. P. 65–70. doi: 10.1051/parasite/2006131065

[39] Khamboonruang C. The present status of trichinellosis in Thailand. Southeast Asian J Trop Med Public Health. 1991;22 Suppl:312–315.

[40] Khamboonruang C. The present status of trichinellosis in Thailand // The Southeast Asian Journal of Tropical Medicine and Public Health. 1991. Vol. 22. Suppl. P. 312–315.

[41] Lo YC, Hung CC, Lai CS, et al. Human trichinosis after consumption of soft-shelled turtles, Taiwan. Emerging Infect Dis. 2009;15(12):2056–2058. doi: 10.3201/eid1512.090619

[42] Lo Y.C., Hung C.C., Lai C.S., et al. Human trichinosis after consumption of soft-shelled turtles, Taiwan // Emerging Infectious Diseases. 2009. Vol. 15, N 12. P. 2056–2058. doi: 10.3201/eid1512.090619

[43] Bruschi F, Korenaga M, Watanabe N. Eosinophils and Trichinella infection: toxic for the parasite and the host? Trends in Parasitology. 2008;24(10):462–467. doi: 10.1016/j.pt.2008.07.001

[44] Bruschi F., Korenaga M., Watanabe N. Eosinophils and Trichinella infection: toxic for the parasite and the host? // Trends in Parasitology. 2008. Vol. 24, N 10. P. 462–467. doi: 10.1016/j.pt.2008.07.001

[45] Pozio E, Sacchini D, Sacchi L, et al. Failure of mebendazole in the treatment of humans with Trichinella spiralis infection at the stage of encapsulating larvae. Clin Infect Dis. 2001;32(4):638–642. doi: 10.1086/318707

[46] Pozio E., Sacchini D., Sacchi L., et al. Failure of mebendazole in the treatment of humans with Trichinella spiralis infection at the stage of encapsulating larvae // Clinical Infectious Diseases. 2001. Vol. 32, N 4. P. 638–642. doi: 10.1086/318707

[47] Fröscher W, Gullotta F, Saathoff M, Tackmann W. Chronic trichinosis. Clinical, bioptic, serological and electromyographic observations. Eur Neurol. 1988;28(4):221–226. doi: 10.1159/000116271

[48] Fröscher W., Gullotta F., Saathoff M., Tackmann W. Chronic trichinosis. Clinical, bioptic, serological and electromyographic observations // European Neurology. 1988. Vol. 28, N 4. P. 221–226. doi: 10.1159/000116271

[49] Neghina R, Neghina AM, Marincu I, Iacobiciu I. Cardiac involvement in patients with trichinosis hospitalized in western Romania. Foodborne Pathogens Dis. 2010;7(10):1235–1238. doi: 10.1089/fpd.2010.0573

[50] Neghina R., Neghina A.M., Marincu I., Iacobiciu I. Cardiac involvement in patients with trichinosis hospitalized in western Romania // Foodborne Pathogens and Disease. 2010. Vol. 7. N 10. P. 1235–1238. doi: 10.1089/fpd.2010.0573

[51] Na HR, Zhu X, Stewart GL, Seelig LL Jr. Ethanol consumption suppresses cell-mediated inflammatory responses and increases T-helper type 2 cytokine secretion in Trichinella spiralis-infected rats. Alcoholism: Clinical and Experimental Research. 1997;21(7):1179–1185.

[52] Na H.R., Zhu X., Stewart G.L., Seelig L.L. Jr. Ethanol consumption suppresses cell-mediated inflammatory responses and increases T-helper type 2 cytokine secretion in Trichinella spiralis-infected rats // Alcoholism: Clinical and Experimental Research. 1997. Vol. 21, N 7. P. 1179–1185.

[53] Pak SG, Belaya OF, Malov VA, et al. Experience and prospects of studying the syndrome of intoxication in infectious pathology. Jornal Infektologii. 2009;1(1):9–17. (In Russ).

[54] Пак С.Г., Белая О.Ф., Малов В.А. и др. Опыт и перспективы изучения синдрома интоксикации в инфекционной патологии // Журнал инфектологии. 2009. Т. 1, № 1. С. 9–17.

[55] Todd JW. Trichinosis [letter]. Br Med J. 1979;1(6174):1355. doi: 10.1136/bmj.1.6174.1355

[56] Todd J.W. Trichinosis [letter] // Br Med J. 1979. Vol. 1, N 6174. P. 1355. doi: 10.1136/bmj.1.6174.1355

[57] Pustovoit VI, Adoeva EYa, Kozlov SS, et al. Morphological changes in the striated muscles after Albendazole treatment for experimental trichinosis. Medical Parasitology and parasitic diseases. 2015;(2):32–35. (In Russ).

[58] Пустовойт В.И., Адоева Е.Я., Козлов С.С. и др. Морфологические изменения в поперечнополосатой мускулатуре после лечения албендазолом экспериментального трихинеллеза // Медицинская паразитология и паразитарные болезни. 2015. № 2. C. 32–35.

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