EVALUATION OF REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF DOMESTIC VACCINE

I. V. Feldblium; M. G Menshikova; T. V Danilina; I. A OkunevaJ; O. A Perminova; V. V Semerikov; K. A Pavroz

doi:10.17816/EID40767

Epidemiology and Infectious Diseases ›› 2013, Vol. 18 ›› Issue (4) : 53 -57. DOI: 10.17816/EID40767

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EVALUATION OF REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF DOMESTIC VACCINE "ENCEVIR» WITH A REDUCED ANTIGEN LOAD IN IMMUNIZATION OF CHILDREN 3-17 YEARS OLD ACCORDINGLY TO EMERGENCY VACCINATION PROTOCOL

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Abstract

The article presents the results of the open comparative randomized clinical study performed in children aged 3 to 17 years which were immunized with the Russian vaccine «EnceVir»® possessing the reduced antigenic load accordingly to emergency vaccination protocol. The aim of the study was to assess reactogenicity, safety and immunogenicity of the vaccine. The vaccine is characterized by a low reactogenicity profile, the high profile of safety, adequate immunogenicity, and it is not yielding to foreign vaccine «FSME-Immun Inject / Junior»

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Vaccine «Encevir»® (0 / 25 ml) / emergency vaccination protocol / reactogenicity / safety / immunogenicity

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I. V. Feldblium, M. G Menshikova, T. V Danilina, I. A OkunevaJ, O. A Perminova, V. V Semerikov, K. A Pavroz. EVALUATION OF REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF DOMESTIC VACCINE "ENCEVIR» WITH A REDUCED ANTIGEN LOAD IN IMMUNIZATION OF CHILDREN 3-17 YEARS OLD ACCORDINGLY TO EMERGENCY VACCINATION PROTOCOL. Epidemiology and Infectious Diseases, 2013, 18(4): 53-57 DOI:10.17816/EID40767

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