Lifetime diagnosis of adrenal hemorrhage in an infant with meningococcal infection

Inna Nikolaevna Lastovka; Maksim Dmitrievich Ocheretniy; Vladimir Arkad'evich Matveev; I N Lastovka; M D Ocheretniy; V A Matveyev

doi:10.17816/EID40493

Epidemiology and Infectious Diseases ›› 2010, Vol. 15 ›› Issue (4) : 44 -46. DOI: 10.17816/EID40493

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Lifetime diagnosis of adrenal hemorrhage in an infant with meningococcal infection

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Abstract

The generalized forms of meningococcal infection are a serious health care problem. Fulminant meningococcemia is a form of infection with extremely rapid progression and high mortality, which more frequently occurs in infants of the first year of life. Autopsy study revealed bilateral adrenal hemorrhage (hemorrhagic necrosis). Acute adrenal insufficiency requires the administration of glucocorticosteroids (GCS) in particularly severe forms of meningococcemia. However, it is unadvisable to use GCS in patients with infectious toxic shock in the absence of adrenal insufficiency as it fails to affect survival in the early period and increases death rates in the late period due to the fact that superinfections may develop. Ultrasonography may be useful in detecting adrenal hemorrhagic necrosis in a patient with meningococcal infection just on his/her admission and in making an immediate decision to initiate GCS therapy. The paper describes a case of the lifetime diagnosis of adrenal hemorrhage in a paper with fulminant meningococcemia.

Keywords

meningococcal infection / fulminant meningococcemia / adrenal hemorrhage / adrenal ultrasonography / hemorrhagic necrosis

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Inna Nikolaevna Lastovka, Maksim Dmitrievich Ocheretniy, Vladimir Arkad'evich Matveev, I N Lastovka, M D Ocheretniy, V A Matveyev. Lifetime diagnosis of adrenal hemorrhage in an infant with meningococcal infection. Epidemiology and Infectious Diseases, 2010, 15(4): 44-46 DOI:10.17816/EID40493

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References

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[1]	Детская ультразвуковая диагностика / Под ред. М. И. Пыкова, К. В. Ватолина. - M., 2001.

[2]	Избранные лекции по анестезиологии и интенсивной терапии детского возраста: Учеб.-метод, пособие / Курек В. В. и др. - Минск, 2002. - Ч. 2.

[3]	Клиническое руководство по ультразвуковой диагностике / Под ред. В. В. Митькова. - М., 1996. - Т. 1.

[4]	Курек В. В., Кулагин А. Е. Руководство по неотложным состояниям у детей. - М., 2008.

[5]	Матвеев В. А., Хулуп Г. Я. Эпидемиология, клиника, диагностика, лечение и профилактика менингококковой инфекции у детей. Возможности УЗ-исследований при выявлении контингента, особо угрожаемого по развитию молниеносной менингококкемии. - Минск, 2007.

[6]	Менингококковая инфекция: клиника, тактика, лечение: Метод. рекомендации // Жаворонок С. В., Евдолюк С. В., Семенюк Л. Н. и др. - Гомель, 2005.

[7]	Тяжелые и молниеносные формы менингококковой инфекции у детей. Современные принципы прогнозирования исхода интенсивной терапии / Георгиянц М. А. и др. - Минск, 2007.

[8]	Dellinger R. P., Levy M. M., Carlet J. M. et al. Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 // Crit. Care Med. - 2008. - Vol. 36, N 1. - P. 296-327.

[9]	van Deuren M., Brandtzaeg P., van der Meer J. Update on meningococcal disease with emphasis on pathogenesis and clinical management // Clin. Microbiol. Rev. - 2000. - Vol. 13, N 1. - P. 144-166.