LIVER BIOPSY IN CHILDRENS WITH CHRONIC LIVER PATHOLOGIES. CLINICAL OBSERVATIONS
P. V. Khrolenko , E. Yu. D'yakonova , A. N. Surkov , I. V. Dvoryakovsky , K. A. Kulikov
Russian Journal of Pediatric Surgery ›› 2020, Vol. 24 ›› Issue (1) : 40 -44.
LIVER BIOPSY IN CHILDRENS WITH CHRONIC LIVER PATHOLOGIES. CLINICAL OBSERVATIONS
Chronic liver diseases in children are characterized by a progressive course and lead to fibrotic changes in the organ up to cirrhotic transformation. Therapy effectiveness and patient’s quality of life depend on timely verified diagnosis and stage of the process. Morphological examination of hepatobiopsies remains a key issue in the diagnostics of histopathological changes in the liver; however, biopsy sampling is associated with a risk of complications and does not exclude insufficiently informative biopsies. This article discusses three clinical cases of patients in whom a personalized choice of the way of biopsy sampling allowed to avoid life-threatening complications and to obtain the most informative biopsy material.
chronic liver disease / liver biopsy / children
| [1] |
Белобородова Е.В., Белобородова Э.И., Пурлик И.Л., Калачева Т.П. Состояние печени при хронических гепатитах различной этиологии (по данным морфологического исследования биоптатов печени). Клинические перспективы гастроэнтерологии, гепатологии. 2014; 1: 31-36. |
| [2] |
Патлусов Е.П., Борзунов В.М., Кузнецов П.Л., Чернов В.С. Сравнительная характеристика инвазивных и неинвазивных методов диагностики стадии фиброза печени у пациентов с хроническими вирусными гепатитами. Медицинский вестник Министерства внутренних дел. 2014; 3: 53-56. |
| [3] |
Nousbaum J.B., Cadranel J.F., Bonnemaison G., Bourlière M., Chiche L., Chor H., Denninger M.H., Degos F., Jacquemin E., Le Bail B., Loustaud-Ratti V., Pelletier G., Soyer P., Zins M. Clinical practice guidelines on the use of liver biopsy. Gastroenterol Clin Biol. 2002; 26(10): 848-878 |
| [4] |
Фокин Д.В., Дударев В.А., Киргизов И.В., Складнева В.О. Лечение очаговых образований печени у детей. Детская хирургия. 2013; 2: 11-14. |
| [5] |
Циммерман Я.С. Фиброз печени: патогенез, методы диагностики, перспективы лечения. Клиническая фармакология и терапия. 2017; 26 (1): 54-58. |
| [6] |
Pokorska-Śpiewak M, Kowalik-Mikołajewska B, Aniszewska M, et al. Is liver biopsy still needed in children with chronic viral hepatitis? World J Gastroenterol. 2015; 21(42): 12141-9. |
| [7] |
Ingram K. Diagnostic liver biopsy technique [Internet]. Medscape; 2017 Available from: https://emedicine.medscape.com/article/1819437-overview. |
| [8] |
Sheriff S., Cammel G., Carey W.D. et al. The role of liver biopsy in chronic hepatitis C. Hepatology. 2001; 33(1): 196-200. |
| [9] |
Маев И.В. Биопсия печени. Учебно-методическое пособие. М.: Медгиз. 2002; 28 с |
/
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