TO THE QUESTION OF THE TERATOGENESIS OF GASTROSCHISIS

M. P. Razin , L. M. Zheleznov

Russian Journal of Pediatric Surgery ›› 2018, Vol. 22 ›› Issue (6) : 321 -322.

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Russian Journal of Pediatric Surgery ›› 2018, Vol. 22 ›› Issue (6) :321 -322. DOI: 10.18821/1560-9510-2018-22-6-321-322
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TO THE QUESTION OF THE TERATOGENESIS OF GASTROSCHISIS

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Abstract

Gastroschisis is a severe congenital malformation of the development, characterized by celosoma (defect in the anterior abdominal wall and intrauterine intestinal eventration). The origin of the malformation is currently not fully investigated. Most authors consider the cause of gastroschisis to be a violation of the formation of the anterior abdominal wall, in contrast to omphalocele, which is unanimously considered a malrotation of the first period of rotation of the midgut. The authors compare known facts about gastroschisis and new literary (including experimental) data. The analysis allows us to conclude gastroschisis to be an associated defect of intestinal malrotation and development of the anterior abdominal wall.

Keywords

gastroschisis / malrotation / newborns

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M. P. Razin, L. M. Zheleznov. TO THE QUESTION OF THE TERATOGENESIS OF GASTROSCHISIS. Russian Journal of Pediatric Surgery, 2018, 22(6): 321-322 DOI:10.18821/1560-9510-2018-22-6-321-322

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