Assessment of the dynamics of concentration of biomarkers of acute kidney injury in remote shock wave lithotripsy in children

Abstract

BACKGROUND: For several decades, remote shock wave lithotripsy has been considered a universally recognized gold standard for the treatment of upper urinary tract concrements. Despite its noninvasiveness, each lithotripsy session causes acute kidney injury which cannot be reliably assessed with traditional indicators used in nephrourology. Currently, new modern indicators found in the urine and serum are thought to be more informative biomarkers. In this paper, we investigated the effectiveness of some of them for possible potentials in the diagnostics of acute kidney injury in remote lithotripsy.

AIM: To evaluate changes in acute kidney injury biomarkers during remote shock wave lithotripsy in children.

MATERIALS AND METHODS: 54 children with urolithiasis, who had a session of remote shock wave lithotripsy, were enrolled in the study. In all patients, samples of urine and blood serum were taken three times for assessing biomarkers concentration: before lithotripsy session, after 45 min and after 24 h.

RESULTS: Statistically significant changes in the concentration of all urine biomarkers (NGAL, L-FABP, TIMP-2, calbindin-D, KIM-1) were registered at the basal level and 45 min after the procedure. A number of markers studied by us in the blood serum showed more significant changes 24 h after the procedure (IL-18, TNF-α). Although IGFBP-1 concentration increased slightly after 45 min, this change was not statistically significant (p <0.781). The level of cystatin C did not increase after lithotripsy.

CONCLUSION: The performed analysis of changes in biomarkers concentration has revealed a sufficiently high informative value of biomarkers in assessing the degree of acute kidney injury during remote lithotripsy in children. It also allows to suggest that the studied biomarkers may be promising indicators characterizing such an injury.

Keywords

pediatric surgery / pediatric urology / urolithiasis / urinary concrements / surgical treatment / remote shock wave lithotripsy / acute kidney injury / biomarkers of injury / biomarkers of inflammation / children

References

[1] Gadzhiev N, Prosyannikov M, Malkhasyan V, et al. Urolithiasis prevalence in the Russian Federation: Analysis of trends over a 15-year period. World J Urol. 2021;39(10):3939-3944. EDN: SUSDKJ doi: 10.1007/s00345-021-03729-y

[2] Gadzhiev N., Prosyannikov M., Malkhasyan V., et al. Urolithiasis prevalence in the Russian Federation: Analysis of trends over a 15-year period // World J Urol. 2021. Vol. 39, N 10. P. 3939-3941. EDN: SUSDKJ doi: 10.1007/s00345-021-03729-y

[3] Talso M, Tefik T, Mantica G, et al. Extracorporeal shockwave lithotripsy: Current knowledge and future perspectives. Minerva Urol Nefrol. 2019;71(4):365-372. doi: 10.23736/S0393-2249.19.03415-5

[4] Talso M., Tefik T., Mantica G., et al. Extracorporeal shockwave lithotripsy: Current knowledge and future perspectives // Minerva Urol Nefrol. 2019. Vol. 71, N 4. P. 365-372. doi: 10.23736/S0393-2249.19.03415-5

[5] Zorkin SN, Nikulin OD, Shahnovskiy DS. Remote shock wave lithotripsy in the treatment of urolithiasis in children: Types and possibilities. Detskaya khirurgiya (Russian Journal of Pediatric Surgery). 2023;26(6):321-326. EDN: IYZCXD doi: 10.55308/1560-9510-2022-26-6-321-326

[6] Зоркин С.Н., Никулин О.Д., Шахновский Д.С. Дистанционная ударно-волновая литотрипсия в лечении мочекаменной болезни у детей: виды и возможности (обзор литературы) // Детская хирургия. 2022. Т. 26, № 6. С. 321-326. EDN: IYZCXD doi: 10.55308/1560-9510-2022-26-6-321-326

[7] Hughes SF, Jones N, Thomas-Wright SJ, et al. Shock wave lithotripsy, for the treatment of kidney stones, results in changes to routine blood tests and novel biomarkers: A prospective clinical pilot-study. Eur J Med Res. 2020;25(1):18. doi: 10.1186/s40001-020-00417-2

[8] Hughes S.F., Jones N., Thomas-Wright S.J., et al. Shock wave lithotripsy, for the treatment of kidney stones, results in changes to routine blood tests and novel biomarkers: A prospective clinical pilot-study // Eur J Med Res. 2020. Vol. 25, N 1. P. 18. doi: 10.1186/s40001-020-00417-2

[9] Milišić E, Alić J, Zvizdić Z, et al. Urinary neutrophil gelatinase-associated lipocalin level as a biomarker of acute kidney injury following extracorporeal shock wave lithotripsy. Cent Eur J Urol. 2021;74(4):579-587. EDN: DPGUHH doi: 10.5173/ceju.2021.0174

[10] Milišić E., Alić J., Zvizdić Z., et al. Urinary neutrophil gelatinase-associated lipocalin level as a biomarker of acute kidney injury following extracorporeal shock wave lithotripsy // Cent European J Urol. 2021. Vol. 74, N 4. P. 579-587. EDN: DPGUHH doi: 10.5173/ceju.2021.0174

[11] Nazarov TK, Komyakov BK, Rychkov IV, et al. Role of biomarkers of acute kidney damage during lithotripsy of high-density stones. Urologiia. 2019;(1):23-27. EDN: FKKLMH doi: 10.18565/urology.2019.1.23-27

[12] Назаров Т.Х., Комяков Б.К., Рычков И.В., и др. Роль маркеров острого повреждения почек при проведении литотрипсии конкрементов высокой плотности // Урология. 2019. № 1. С. 23-27. EDN: FKKLMH doi: 10.18565/urology.2019.1.23-27

[13] Clark DL, Connors BA, Evan AP, et al. Localization of renal oxidative stress and inflammatory response after lithotripsy. BJU Int. 2009;103(11):1562-1568. doi: 10.1111/j.1464-410X.2008.08260.x

[14] Clark D.L., Connors B.A., Evan A.P., et al. Localization of renal oxidative stress and inflammatory response after lithotripsy // BJU Int. 2009. Vol. 103, N 11. P. 1562-1568. doi: 10.1111/j.1464-410X.2008.08260.x

[15] Krambeck AE, Gettman MT, Rohlinger AL, et al. Diabetes mellitus and hypertension associated with shock wave lithotripsy of renal and proximal ureteral stones at 19 years of followup. J Urol. 2006;175(5):1742-1747. doi: 10.1016/S0022-5347(05)00989-4

[16] Krambeck A.E., Gettman M.T., Rohlinger A.L., et al. Diabetes mellitus and hypertension associated with shock wave lithotripsy of renal and proximal ureteral stones at 19 years of followup // J Urol. 2006. Vol. 175, N 5. P. 1742-1747. doi: 10.1016/S0022-5347(05)00989-4

[17] Wu Q, Liang R, Huang Y, et al. Association between renal urolithiasis after extracorporeal shock wave lithotripsy therapy and new-onset hypertension: An updated meta-analysis. J Int Med Res. 2021;49(4):3000605211002003. doi: 10.1177/03000605211002003

[18] Wu Q., Liang R., Huang Y., et al. Association between renal urolithiasis after extracorporeal shock wave lithotripsy therapy and new-onset hypertension: An updated meta-analysis // J Int Med Res. 2021. Vol. 49, N 4. P. 3000605211002003. doi: 10.1177/03000605211002003

[19] Dzięgała M, Krajewski W, Kołodziej A, et al. Evaluation and physiopathology of minor transient shock wave lithotripsy--induced renal injury based on urinary biomarkers levels. Cent Eur J Urol. 2018;71(2):214-220. doi: 10.5173/ceju.2018.1629

[20] Dzięgała M., Krajewski W., Kołodziej A., et al. Evaluation and physiopathology of minor transient shock wave lithotripsy--induced renal injury based on urinary biomarkers levels // Cent European J Urol. 2018. Vol. 71, N 2. P. 214-220. doi: 10.5173/ceju.2018.1629

[21] Willis LR, Evan AP, Connors BA, et al. Relationship between kidney size, renal injury, and renal impairment induced by shock wave lithotripsy. J Am Soc Nephrol. 1999;10(8):1753-1762. doi: 10.1681/ASN.V1081753

[22] Willis L.R., Evan A.P., Connors B.A., et al. Relationship between kidney size, renal injury, and renal impairment induced by shock wave lithotripsy // J Am Soc Nephrol. 1999. Vol. 10, N 8. P. 1753-1762. doi: 10.1681/ASN.V1081753

[23] Dalton RN. Serum creatinine and glomerular filtration rate: perception and reality. Clin Chem. 2010;56(5):687-689. doi: 10.1373/clinchem.2010.144261

[24] Dalton R.N. Serum creatinine and glomerular filtration rate: Perception and reality // Clin Chem. 2010. Vol. 56, N 5. P. 687-689. doi: 10.1373/clinchem.2010.144261

[25] Liu X, Guan Y, Xu S, et al. Early predictors of acute kidney injury: A narrative review. Kidney Blood Press Res. 2016;41(5):680-700. doi: 10.1159/000447937

[26] Liu X., Guan Y., Xu S., et al. Early predictors of acute kidney injury: A narrative review // Kidney Blood Press Res. 2016. Vol. 41, N 5. P. 680-700. doi: 10.1159/000447937

[27] Oh DJ. A long journey for acute kidney injury biomarkers. Ren Fail. 2020;42(1):154-165. doi: 10.1080/0886022X.2020.1721300

[28] Oh D.J. A long journey for acute kidney injury biomarkers // Ren Fail. 2020. Vol. 42, N 1. P. 154-165. doi: 10.1080/0886022X.2020.1721300

[29] Wołyniec W, Ratkowski W, Renke J, Renke M. Changes in novel AKI biomarkers after exercise: A systematic review. Int J Mol Sci. 2020;21(16):5673 doi: 10.3390/ijms21165673

[30] Wołyniec W., Ratkowski W., Renke J., Renke M. Changes in novel AKI biomarkers after exercise. A systematic review // Int J Mol Sci. 2020. Vol. 21, N 16. P. 5673. doi: 10.3390/ijms21165673

[31] Annamalai SK, Kapur NK. Contrast induced nephropathy after coronary or vascular intervention: More biomarkers than answers. Catheter Cardiovasc Interv. 2018;91(7):1192-1193. doi: 10.1002/ccd.27671

[32] Annamalai S.K., Kapur N.K. Contrast induced nephropathy after coronary or vascular intervention: More biomarkers than answers // Catheter Cardiovasc Interv. 2018. Vol. 91, N 7. P. 1192-1193. doi: 10.1002/ccd.27671

[33] Yuan SM. Acute kidney injury after cardiac surgery: Risk factors and novel biomarkers. Braz J Cardiovasc Surg. 2019;34(3):352-360. doi: 10.21470/1678-9741-2018-0212

[34] Yuan S.M. Acute kidney injury after cardiac surgery: Risk factors and novel biomarkers // Braz J Cardiovasc Surg. 2019. Vol. 34, N 3. P. 352-360. doi: 10.21470/1678-9741-2018-0212

[35] Zhang YL, Qiao SK, Wang RY, Guo XN. NGAL attenuates renal ischemia/reperfusion injury through autophagy activation and apoptosis inhibition in rats. Chem Biol Interact. 2018;(289):40-46. doi: 10.1016/j.cbi.2018.04.018

[36] Zhang Y.L., Qiao S.K., Wang R.Y., Guo X.N. NGAL attenuates renal ischemia/reperfusion injury through autophagy activation and apoptosis inhibition in rats // Chem Biol Interact. 2018. N 289. P. 40-46. doi: 10.1016/j.cbi.2018.04.018

[37] Kachko A, Costafreda MI, Zubkova I, et al. Determinants in the Ig variable domain of human HAVCR1 (TIM-1) are required to enhance hepatitis C virus entry. J Virol. 2018;92(6):e01742-17. EDN: YFLEPB doi: 10.1128/JVI.01742-17

[38] Kachko A., Costafreda M.I., Zubkova I., et al. Determinants in the Ig variable domain of human HAVCR1 (TIM-1) are required to enhance hepatitis C virus entry // J Virol. 2018. Vol. 92, N 6. P. e01742-17. EDN: YFLEPB doi: 10.1128/JVI.01742-17

[39] Bank JR, van der Pol P, Vreeken D, et al. Kidney injury molecule-1 staining in renal allograft biopsies 10 days after transplantation is inversely correlated with functioning proximal tubular epithelial cells. Nephrol Dialysis Transplant. 2017;32(12):2132-2141. doi: 10.1093/ndt/gfx286

[40] Bank J.R., van der Pol P., Vreeken D., et al. Kidney injury molecule-1 staining in renal allograft biopsies 10 days after transplantation is inversely correlated with functioning proximal tubular epithelial cells // Nephrol Dialysis Transplant. 2017. Vol. 32, N 12. P. 2132-2141. doi: 10.1093/ndt/gfx286

[41] Miroshkina IV, Grickevich AA, Baytman TP, et al. The role of markers of acute kidney damage in assessing kidney function with its ischemia. Exp Clin Urol. 2018;(4):114-121. EDN: VRTKPJ

[42] Мирошкина И.В., Грицкевич А.А., Байтман Т.П., и др. Роль маркеров острого повреждения почки в оценке функции почки при ее ишемии // Экспериментальная и клиническая урология. 2018. № 4. С. 114-121. EDN: VRTKPJ

[43] Lin X, Yuan J, Zhao Y, Zha Y. Urine interleukin-18 in prediction of acute kidney injury: A systemic review and meta-analysis. J Nephrol. 2015;28(1):7-16. EDN: YZOJLD doi: 10.1007/s40620-014-0113-9

[44] Lin X., Yuan J., Zhao Y., Zha Y. Urine interleukin-18 in prediction of acute kidney injury: A systemic review and meta-analysis // J Nephrol. 2015. Vol. 28, N 1. P. 7-16. EDN: YZOJLD doi: 10.1007/s40620-014-0113-9

[45] Wang S, Zhang Z, Wang J, Miao H. MiR-107 induces TNF-α secretion in endothelial cells causing tubular cell injury in patients with septic acute kidney injury. Biochem Biophys Res Commun. 2017;483(1):45-51. doi: 10.1016/j.bbrc.2017.01.013

[46] Wang S., Zhang Z., Wang J., Miao H. MiR-107 induces TNF-α secretion in endothelial cells causing tubular cell injury in patients with septic acute kidney injury // Biochem Biophys Res Commun. 2017. Vol. 483, N 1. P. 45-51. doi: 10.1016/j.bbrc.2017.01.013

[47] Yamamoto T, Noiri E, Ono Y, et al. Renal L-type fatty acid-binding protein in acute ischemic injury. J Am Soc Nephrol. 2007;18(11):2894-2902. doi: 10.1681/ASN.2007010097

[48] Yamamoto T., Noiri E., Ono Y., et al. Renal L-type fatty acid-binding protein in acute ischemic injury // J Am Soc Nephrol. 2007. Vol. 18, N 11. P. 2894-2902. doi: 10.1681/ASN.2007010097

[49] Schrezenmeier EV, Barasch J, Budde K, et al. Biomarkers in acute kidney injury--pathophysiological basis and clinical performance. Acta Physiologica. 2017;219(3):556-574. EDN: YVTLYF doi: 10.1111/apha.12764

[50] Schrezenmeier E.V., Barasch J., Budde K., et al. Biomarkers in acute kidney injury--pathophysiological basis and clinical performance // Acta Physiologica. 2017. Vol. 219, N 3. P. 556-574. EDN: YVTLYF doi: 10.1111/apha.12764

[51] Fagerberg L, Hallström BM, Oksvold P, et al. Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Mol Cell Proteomics. 2014;13(2):397-406. EDN: MTOMUS doi: 10.1074/mcp.M113.035600

[52] Fagerberg L., Hallström B.M., Oksvold P., et al. Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics // Mol Cell Proteomics. 2014. Vol. 13, N 2. P. 397-406. EDN: MTOMUS doi: 10.1074/mcp.M113.035600

[53] Ortega LM, Heung M. The use of cell cycle arrest biomarkers in the early detection of acute kidney injury. Is this the new renal troponin? Nefrología (Engl Ed). 2018;38(4):361-367. doi: 10.1016/j.nefro.2017.11.013

[54] Ortega L.M., Heung M. The use of cell cycle arrest biomarkers in the early detection of acute kidney injury. Is this the new renal troponin? // Nefrología (Engl Ed). 2018. Vol. 38, N 4. P. 361-367. doi: 10.1016/j.nefro.2017.11.013

[55] Emlet DR, Pastor-Soler N, Marciszyn A, et al. Insulin-like growth factor binding protein 7 and tissue inhibitor of metalloproteinases-2: Differential expression and secretion in human kidney tubule cells. Am J Physiol Renal Physiol. 2017;312(2):F284-296. EDN: YXCIST doi: 10.1152/ajprenal.00271.2016

[56] Emlet D.R., Pastor-Soler N., Marciszyn A., et al. Insulin-like growth factor binding protein 7 and tissue inhibitor of metalloproteinases-2: Differential expression and secretion in human kidney tubule cells // Am J Physiol Renal Physiol. 2017. Vol. 312, N 2. P. F284-296. EDN: YXCIST doi: 10.1152/ajprenal.00271.2016

[57] Johnson AC, Zager RA. Mechanisms underlying increased TIMP2 and IGFBP7 urinary excretion in experimental AKI. J Am Soc Nephrol. 2018;29(8):2157-2167. doi: 10.1681/ASN.2018030265

[58] Johnson A.C., Zager R.A. Mechanisms underlying increased TIMP2 and IGFBP7 urinary excretion in experimental AKI // J Am Soc Nephrol. 2018. Vol. 29, N 8. P. 2157-2167. doi: 10.1681/ASN.2018030265

[59] Lane BR, Babitz SK, Vlasakova K, et al. Evaluation of urinary renal biomarkers for early prediction of acute kidney injury following partial nephrectomy: A feasibility study. Eur Urol Focus. 2020;6(6):1240-1247. doi: 10.1016/j.euf.2018.10.017

[60] Lane B.R., Babitz S.K., Vlasakova K., et al. Evaluation of urinary renal biomarkers for early prediction of acute kidney injury following partial nephrectomy: A feasibility study // Eur Urol Focus. 2020. Vol. 6, N 6. P. 1240-1247. doi: 10.1016/j.euf.2018.10.017

[61] George B, Szilagyi JT, Joy MS, Aleksunes LM. Regulation of renal calbindin expression during cisplatin-induced kidney injury. J Biochem Mol Toxicol. 2022;36(7):e23068. EDN: FQRRTU doi: 10.1002/jbt.23068

[62] George B., Szilagyi J.T., Joy M.S., Aleksunes L.M. Regulation of renal calbindin expression during cisplatin-induced kidney injury // J Biochem Mol Toxicol. 2022. Vol. 36, N 7. P. e23068. EDN: FQRRTU doi: 10.1002/jbt.23068

[63] Vittori M, Baroni S, Ferraro PM, et al. Neutrophil gelatinase-associated lipocalin (NGAL) value changes before and after shock wave lithotripsy. Urolithiasis. 2017;45(4):347-351. doi: 10.1007/s00240-016-0932-3

[64] Vittori M., Baroni S., Ferraro P.M., et al. Neutrophil gelatinase-associated lipocalin (NGAL) value changes before and after shock wave lithotripsy // Urolithiasis. 2017. Vol. 45, N 4. P. 347-351. doi: 10.1007/s00240-016-0932-3

[65] Kardakos IS, Volanis DI, Kalikaki A, et al. Evaluation of neutrophil gelatinase-associated lipocalin, interleukin-18, and cystatin C as molecular markers before and after unilateral shock wave lithotripsy. Urology. 2014;84(4):783-788. doi: 10.1016/j.urology.2014.05.034

[66] Kardakos I.S., Volanis D.I., Kalikaki A., et al. Evaluation of neutrophil gelatinase-associated lipocalin, interleukin-18, and cystatin C as molecular markers before and after unilateral shock wave lithotripsy // Urology. 2014. Vol. 84, N 4. P. 783-788. doi: 10.1016/j.urology.2014.05.034

[67] Codorniu A, Lemasle L, Legrand M, et al. Methods used to assess the performance of biomarkers for the diagnosis of acute kidney injury: A systematic review and meta-analysis. Biomarkers. 2018;23(8):766-772. doi: 10.1080/1354750X.2018.1493616

[68] Codorniu A., Lemasle L., Legrand M., et al. Methods used to assess the performance of biomarkers for the diagnosis of acute kidney injury: A systematic review and meta-analysis // Biomarkers. 2018. Vol. 23, N 8. P. 766-772. doi: 10.1080/1354750X.2018.1493616

[69] Okuda H, Obata Y, Kamijo-Ikemori A, Inoue S. Quantitative and qualitative analyses of urinary L-FABP for predicting acute kidney injury after emergency laparotomy. J Anesth. 2022;36(1):38-45. EDN: AMDCCM doi: 10.1007/s00540-021-03003-w

[70] Okuda H., Obata Y., Kamijo-Ikemori A., Inoue S. Quantitative and qualitative analyses of urinary L-FABP for predicting acute kidney injury after emergency laparotomy // J Anesth. 2022. Vol. 36, N 1. P. 38-45. EDN: AMDCCM doi: 10.1007/s00540-021-03003-w

[71] Griffin BR, Faubel S, Edelstein CL. Biomarkers of drug-induced kidney toxicity. Ther Drug Monit. 2019;41(2):213-226. doi: 10.1097/FTD.0000000000000589

[72] Griffin B.R., Faubel S., Edelstein C.L. Biomarkers of drug-induced kidney toxicity // Ther Drug Monit. 2019. Vol. 41, N 2. P. 213-226. doi: 10.1097/FTD.0000000000000589

[73] Yang J, Lim SY, Kim MG, et al. Urinary tissue inhibitor of metalloproteinase and insulin-like growth factor-7 as early biomarkers of delayed graft function after kidney transplantation. Transplant Proc. 2017;49(9):2050-2054. doi: 10.1016/j.transproceed.2017.09.023

[74] Yang J., Lim S.Y., Kim M.G., et al. Urinary Tissue inhibitor of metalloproteinase and insulin-like growth factor-7 as early biomarkers of delayed graft function after kidney transplantation // Transplant Proc. 2017. Vol. 49, N 9. P. 2050-2054. doi: 10.1016/j.transproceed.2017.09.023

[75] Gunnerson KJ, Shaw AD, Chawla LS, et al. TIMP2/IGFBP7 biomarker panel accurately predicts acute kidney injury in high-risk surgical patients. J Trauma Acute Care Surg. 2016;80(2):243-249. doi: 10.1097/TA.0000000000000912

[76] Gunnerson K.J., Shaw A.D., Chawla L.S., et al. TIMP2/IGFBP7 biomarker panel accurately predicts acute kidney injury in high-risk surgical patients // J Trauma Acute Care Surg. 2016. Vol. 80, N 2. P. 243-249. doi: 10.1097/TA.0000000000000912

[77] George B, Joy MS, Aleksunes LM. Urinary protein biomarkers of kidney injury in patients receiving cisplatin chemotherapy. Exp Biol Med. 2018;243(3):272-282. doi: 10.1177/1535370217745302

[78] George B., Joy M.S., Aleksunes L.M. Urinary protein biomarkers of kidney injury in patients receiving cisplatin chemotherapy // Exp Biol Med. 2018. Vol. 243, N 3. P. 272-282. doi: 10.1177/1535370217745302

[79] Fazel M, Sarveazad A, Mohamed Ali K, et al. Accuracy of urine kidney injury molecule-1 in predicting acute kidney injury in children; a systematic review and meta-analysis. Arch Acad Emerg Med. 2020;8(1):e44.

[80] Fazel M., Sarveazad A., Mohamed Ali K., et al. Accuracy of urine kidney injury molecule-1 in predicting acute kidney injury in children; a systematic review and meta-analysis // Arch Acad Emerg Med. 2020. Vol. 8, N 1. P. e44.

[81] Ng CF, Lo AK, Lee KW, et al. A prospective, randomized study of the clinical effects of shock wave delivery for unilateral kidney stones: 60 versus 120 shocks per minute. J Urol. 2012;188(3):837-842. doi: 10.1016/j.juro.2012.05.009

[82] Ng C.F., Lo A.K., Lee K.W., et al. A prospective, randomized study of the clinical effects of shock wave delivery for unilateral kidney stones: 60 versus 120 shocks per minute // J Urol. 2012. Vol. 188, N 3. P. 837-842. doi: 10.1016/j.juro.2012.05.009

[83] Bantis A, Tsakaldimis G, Zissimopoulos A, et al. Can tumor necrosis factor a (TNF-a) and interleukin 6 (IL-6) be used as prognostic markers of infection following ureteroscopic lithrotripsy and extracorporeal shock wave lithotripsy for ureteral stones? Hell J Nucl Med. 2015;18(Suppl 1):160.

[84] Bantis A., Tsakaldimis G., Zissimopoulos A., et al. Can tumor necrosis factor a (TNF-a) and interleukin 6 (IL-6) be used as prognostic markers of infection following ureteroscopic lithrotripsy and extracorporeal shock wave lithotripsy for ureteral stones? // Hell J Nucl Med. 2015. Vol. 18, Suppl. 1. P. 160.

[85] Yuan SM. Acute kidney injury after cardiac surgery: Risk factors and novel biomarkers. Braz J Cardiovasc Surg. 2019;34(3):352-360. doi: 10.21470/1678-9741-2018-0212

[86] Yuan S.M. Acute kidney injury after cardiac surgery: Risk factors and novel biomarkers // Braz J Cardiovasc Surg. 2019. Vol. 34, N 3. P. 352-360. doi: 10.21470/1678-9741-2018-0212

[87] Gan J, Zhou X. Comparison of urine neutrophil gelatinase-associated lipocalin and interleukin-18 in prediction of acute kidney injury in adults. Medicine. 2018;97(39):e12570. doi: 10.1097/MD.0000000000012570

[88] Gan J., Zhou X. Comparison of urine neutrophil gelatinase-associated lipocalin and interleukin-18 in prediction of acute kidney injury in adults // Medicine. 2018. Vol. 97, N 39. P. e12570. doi: 10.1097/MD.0000000000012570

[89] Pan HC, Yang SY, Chiou TT, et al. Comparative accuracy of biomarkers for the prediction of hospital-acquired acute kidney injury: A systematic review and meta-analysis. Crit Care. 2022;26(1):349. EDN: HEITPL doi: 10.1186/s13054-022-04223-6

[90] Pan H.C., Yang S.Y., Chiou T.T., et al. Comparative accuracy of biomarkers for the prediction of hospital-acquired acute kidney injury: A systematic review and meta-analysis // Crit Care. 2022. Vol. 26, N 1. P. 349. EDN: HEITPL doi: 10.1186/s13054-022-04223-6

[91] Clark DL, Connors BA, Evan AP, et al. Effect of shock wave number on renal oxidative stress and inflammation. BJU Int. 2011;107(2):318-322. doi: 10.1111/j.1464-410X.2010.09311.x

[92] Clark D.L., Connors B.A., Evan A.P., et al. Effect of shock wave number on renal oxidative stress and inflammation // BJU Int. 2011. Vol. 107, N 2. P. 318-322. doi: 10.1111/j.1464-410X.2010.09311.x

[93] Goktas C, Coskun A, Bicik Z, et al. Evaluating ESWL-induced renal injury based on urinary TNF-α, IL-1α, and IL-6 levels. Urol Res. 2012;40(5):569-573. doi: 10.1007/s00240-012-0467-1

[94] Goktas C., Coskun A., Bicik Z., et al. Evaluating ESWL-induced renal injury based on urinary TNF-α, IL-1α, and IL-6 levels // Urol Res. 2012. Vol. 40, N 5. P. 569-573. doi: 10.1007/s00240-012-0467-1

[95] Milišić E, Zvizdić Z, Jonuzi A, et al. Short-term changes in renal function in children and adolescents undergoing extracorporeal shock wave lithotripsy. Med Glas (Zenica). 2019;16(2):224-230. doi: 10.17392/1036-19

[96] Milišić E., Zvizdić Z., Jonuzi A., et al. Short-term changes in renal function in children and adolescents undergoing extracorporeal shock wave lithotripsy // Med Glas (Zenica). 2019. Vol. 16, N 2. P. 224-230. doi: 10.17392/1036-19

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Zorkin S.N., Nikulin O.D., Semikina E.L., Snovskaya M.A., Shakhnovskiy D.S., Bayazitov R.R.