Diffusion tensor imaging in trauma of the cervical spine in children
Dmitriy Dmitrenko , Tolibdzhon Akhadov , Semen Meshcheryakov , Ilya Melnikov , Olga Bozhko , Zhanna Semenova , Maxim Ublinskiy , Natalia Semenova , Andrei Manzhurtsev , Maria Akhlebinina , Tatyana Kostikova , Daria Khusainova
Russian Journal of Pediatric Surgery ›› 2022, Vol. 26 ›› Issue (2)
Diffusion tensor imaging in trauma of the cervical spine in children
Introduction: The technique of diffusion tensor imaging (DTI) is widely used in brain research. However, in studies of the spinal cord, especially in pediatrics, the use of DTI is difficult: the small size of the spinal cord, which is characterized by a low signal-to-noise ratio, artifacts from respiration and pulsation of the heart and large vessels, and swallowing movements. Also, the EPI sequences used to obtain diffusion indices cause eddy current distortion.
Objective: to investigate changes in the parameters of DTI of the spinal cord in children with cervical spinal cord trauma.
Material and methods: 56 children aged 2 to 17 years with cervical spine injury (CSI) and 20 children who did not have CSI were examined using a Phillips Achieva 3 T magnetic resonance scanner. The protocol consisted of sagittal STIR, sagittal and axial T1- and T2WI SE, and axial DTI. For DTI, apparent diffusion coefficient (ADC), fractional anisotropy (FA), axial (AD) and radial (RD) diffusion coefficients were calculated.
Results: According to the ASIA criteria for injuries, out of 56 children, 29 (51%) had CSI with neurological complications, and 27 (49%) had no complications. The degree of neurological dysfunction A was in 13 patients, B - 3, C - 9, D - 4, E - 27 patients. The average values of the group of patients with were: ADC=0.74 ± 0.12*10−3 mm2/s−1, FA = 0.36 ± 0.07, BP=1.15 + 0.28*10−3 mm2/s−1, RD=0.52 + 0.32*10−3 mm2/s−1
Conclusion: DTI can detect changes beyond the limits of conventional MRI. Low ADC values in acute injury may indicate spinal cord injury and predict a negative functional outcome.
children, magnetic resonance tomography, cervical spine, diffusion tensor imaging, trauma
| [1] |
5. Залетина А.В., Виссарионов С.В., Баиндурашвили А.Г., Садовой М.А., Соловьева К.С., Купцова О.А. Структура повреждений позвоночника у детей в регионах Российской Федерации. Хирургия позвоночника. 2017; 14(4): 52-60. doi:10.14531/SS2017.4.52-60 |
| [2] |
6. Ахадов Т.А., Панов В.О., Айхофф У. Травма спинного мозга и позвоночника и ее последствия. In: Магнитно-Резонансная Томография Спинного Мозга и Позвоночника. Москва; 2000:586-633. |
/
| 〈 |
|
〉 |
PDF
