Small cell carcinoma of the ovary of hypercalcemic type: a case report

L. A Ashrafyan , G. A Panshin , Yu. M Bychkov , N. A Babaeva , Svetlana A. Bolshakova

Russian Journal of Oncology ›› 2016, Vol. 21 ›› Issue (4) : 198 -200.

PDF
Russian Journal of Oncology ›› 2016, Vol. 21 ›› Issue (4) : 198 -200. DOI: 10.18821/1028-9984-2016-21-4-198-200
Articles
research-article

Small cell carcinoma of the ovary of hypercalcemic type: a case report

Author information +
History +
PDF

Abstract

The small cell carcinoma of the ovary is a rare tumor with the very modest prognosis. It usually occurs in young women and in two-thirds of cases is associated with hypercalcemia. The treatment combines surgery, chemotherapy, and radiotherapy. Case Presentation. We report a case of small cell carcinoma of the ovary hypercalcemic type in a young Russian woman of 33 years in whom the first manifestations were abdominal pain syndrome. A laparotomy was performed by radical surgery. There were performed 4 courses of chemotherapy, and then conventionally radical operation was executed. Histologically, the diagnosis was confirmed. There was performed palliative chemotherapy, the patient’s death occurred within 10 months after making of the diagnosis. Conclusion. Hypercalcemic type of ovarian cancer is a rare, aggressive tumor with a poor prognosis.

Keywords

ovary / small cell carcinoma / hypercalcemic type / chemotherapy

Cite this article

Download citation ▾
L. A Ashrafyan, G. A Panshin, Yu. M Bychkov, N. A Babaeva, Svetlana A. Bolshakova. Small cell carcinoma of the ovary of hypercalcemic type: a case report. Russian Journal of Oncology, 2016, 21(4): 198-200 DOI:10.18821/1028-9984-2016-21-4-198-200

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Tavassoli F.A., Devilee P., eds. World Health Organization Classification of Tumors. Pathology and Generics of Tumors of the Breast and Female Genital Organs. Lyon: IARS Press; 2003.

[2]

Estel R., Hackethal A., Kalder M. et al. Small cell carcinoma of the ovary of the hypercalcemic type. An analysis of clinical and prognostic aspects of a rare disease on the basis of cases published in the literature. Arch. Gynecol. Obstet. 2011; 284: 1277-82.

[3]

Young R.H., Olivia E., Scully R.E. Small cell carcinoma of the ovary, hypercalcemic type. A clinicopathologic analysis of 150 cases. Am. J. Pathol. 1994; 18: 1102-15.

[4]

Matias-Guin X., Prat J., Young R.H. et al. Human parathyroid hormone-related protein in ovarian small cell carcinoma: an immunohistochemical study. Cancer. 1994; 73 (7): 1878-84.

[5]

Eichhorn J.H., Young R.H., Scully R.E. Primary ovarian small cell carcinoma of pulmonary type. A clinicopathologic, immunohistologic, and flow cytometric analysis of 11 cases. Am. J. Surg. Pathol. 1992; 16: 926-38.

[6]

Münstedt K., Estel R., Dreyer T. et al. Small cell ovarian carcinomas - characterisation of twi rare tumor entities. Geburtsh. Frauenheilk. 2013; 73: 698-704.

[7]

Patsner B., Piver M.S., Lele S.B. Small cell carcinoma of the ovary: a rapidly lethal tumor occuring in the young. Gynecol. Oncol. 1985; 22 (2): 233-9.

[8]

Strosberg J.R., Coppola D., Klimstra O.D. et al. The MANETS consensus guidlelines for the diagnosis and management of poorly differentiated (high-grade) extra-pulmonary neuroendocrinecarcinomas. Pancreas. 2010; 39: 799-800.

[9]

Hann C.L., Rudin C.M. Management of small-cell lung cancer: incremental changes but hope for the future. Oncology (Williston Park). 2008; 22: 1486-92.

[10]

Inadome Y., Shibata T., Suzuki K. et al. Hypercalcemic type ovarian small cell carcinoma with unigue CD 34 expression. Pathol. Int. 2009; 59 (10): 766-8.

[11]

Lamovec J., Bracko M., Cerar O. Familial occurence of small-cell carcinoma of the ovary. Arch. Pathol. Lab. Med. 1995; 119 (6): 523-7.

[12]

Fignon A., Fetissof F., Calais G. et al. Small cell carcinoma of the ovary. A clinical and pathological entity-anotomo. J. Gynecol., Obstet. Biol. Reprod. 1993; 22: 372-8.

[13]

Wynn D., Everett G.D., Boothly R.A. Small cell carcinoma of the ovary with hypercalcemia causes severe pancreatitis and altered mental status. Gynecol. Oncol. 2004; 95 (3): 716-8.

[14]

Harrison M.L., Hoskins P., du Bois A. et al. Small cell carcinoma of the ovary, hypercalcemic type - analysis of combined experience and reccomendation for management. A GCIG study. Gynecol. Oncol. 2006; 100 (2): 233-8.

[15]

Saitoh-Sekiguchi M., Nakahara K., Kozimahara T. et al. Complete remission of ovarian small cell carcinoma treated with irinotecan and cisplatin: a case report. Anticancer Res. 2007; 27: 2685-8.

[16]

Dickersin G.R., Kline I.W., Scully R.E. Small cell carcinoma of the ovary with hypercalcemiia: a report of eleven cases. Cancer. 1982; 49 (1): 188-97.

RIGHTS & PERMISSIONS

Eco-Vector

AI Summary AI Mindmap
PDF

141

Accesses

0

Citation

Detail

Sections
Recommended

AI思维导图

/