Endothelial dysfunction and results of its correction at gastric neoplasm
Sayakhat T. Olzhayev , Ya. N Shoykhet , A. F Lazarev
Russian Journal of Oncology ›› 2015, Vol. 20 ›› Issue (5) : 19 -22.
Endothelial dysfunction and results of its correction at gastric neoplasm
A complex examination of 122 patients with II and III stages of neoplasms were carried out for the purpose of definition of results of correction of disturbances of endothelial functions in operated patients with gastric cancer. All patients were exposed to radical surgical treatment. Endothelium function indicators and contents of circulating endothelial cells were studied. It is revealed that application of L-arginine and ACE inhibitor provides decrease in degree of endothelial dysfunction and damages an endothelium that correlates with decrease in frequency of postoperative complications, late complications in the form of development of recurrence and metastasises and mortality.
gastric cancer / endothelial dysfunction / correction / clinical outcomes
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