Ex vivo comparative study of probe-based confocal laser endomicroscopy and light microscopy in diagnostics of lung cancer

Olesya V. Danilevskaya; A. V Sorokina; A. V Averyanov; F. G Zabozlaev; N. Yu Urazovsky; D. V Sazonov; A. G Sotnikova

doi:10.17816/onco40154

Russian Journal of Oncology ›› 2015, Vol. 20 ›› Issue (3) : 16 -23. DOI: 10.17816/onco40154

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Ex vivo comparative study of probe-based confocal laser endomicroscopy and light microscopy in diagnostics of lung cancer

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Abstract

This study is an ex-vivo comparison of images obtained by probe-based confocal endomicroscopy (pCLE) examination of lung cancer samples and light microscopy specimens prepared from the same samples. This first ex-vivo study revealed endomicroscopic characteristics of different types of lung carcinoma.

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ex vivo confocal laser endomicroscopy / light microscopy / lung cancer / bronchoscopy

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Olesya V. Danilevskaya, A. V Sorokina, A. V Averyanov, F. G Zabozlaev, N. Yu Urazovsky, D. V Sazonov, A. G Sotnikova. Ex vivo comparative study of probe-based confocal laser endomicroscopy and light microscopy in diagnostics of lung cancer. Russian Journal of Oncology, 2015, 20(3): 16-23 DOI:10.17816/onco40154

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[1]	Трахтенберг А.Х., Чиссов В.И. Рак легкого. М.: ГЭОТАР-Медиа, 2009. 13.

[2]	Church T.R., Black W., Aberle D.R., Berg C.D., Clingan K.L., Duan F. et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N.Engl. J. M. 2011; 368: 1980-91.

[3]	Le Goualher G., Genet M., Cave C., Viellerobe B., Berier F., Abrat B., Ayache N. Towards optical biopsies with an integrated fibered confocal fluorescence microscope. Lect. Notes Comput. Sci. 2004; 3217: 761-8.

[4]	Pittayanon R., Rerknimitr R., Wisedopas N., Khemnark S., Thanapirom K., Thienchanachaiya P et al. The learning curve of gastric intestinal metaplasia interpretation on the images obtained by probe-based confocal laser endomicroscopy. J. Diagn. Ther. Endosc. 2012; 2012: 278045.

[5]

Wallace M.B., Crook J.E., Saunders M., Lovat L., Coron E., Waxman I. et al. Multicenter, randomized, controlled trial of confocal laser endomicroscopy assessment of residual metaplasia after mucosal ablation or resection of GI neoplasia in Barrett’s esophagus. J. Gastrointest. Endosc. 2012; 76(3): 539-47.

[6]	Thiberville L., Moreno-Swirc S., Vercauteren T., Peltier E., Cave C., Bourg-Heckly G. In vivo imaging of the bronchial wall microstructure using fibered confocal fluorescence microscopy. Am. J. Respir. Crit. Care Med. 2007; 175: 22-31.

[7]	Thiberville L., Salaun M., Lachkar S., Dominique S., Moreno-Swirc S., Vever-Bizet C., Bourg-Heckly G. Human in-vivo fluorescence microimaging of the alveolar ducts and sacs during bronchoscopy. Eur. Respir. J. 2009; 33: 974-85.

[8]	Meining A., Schwendy S., Becker V., Schmid R.M., Prinz C. In vivo histopathology of lymphocytic colitis. Gastrointest. Endosc. 2007; 66: 398-9.

[9]	Thiberville L, Bourg-Heckly G, Peltier E, Cave C. Per-endoscopic alveolar imaging using fluorescent confocal fibered microscopy. Eur. Respir. J. 2006; 28: Suppl. 50, 155s-6s.

[10]	Stather D.R., MacEachern P, Chee A., Dumoulin E., Tremblay A. Trainee impact on procedural complications: an analysis of 967 consecutive flexible bronchoscopy procedures in an interventional pulmonology practice. Respiration. 2013; 85: 422-8.

[11]	Doria-Rose V.P., White M.C., Klabunde C.N., Nadel M.R., Richards T.B., McNeel T.S. et al. Use of lung cancer screening tests in the United States: results from the 2010 National Health Interview Survey. Cancer Epidemiol. Biomarkers Prev. 2012; 21: 1049-59.

[12]	Аверьянов А.В., Данилевская О.В., Сазонов Д.В., Забозлаев Ф.Г., Кузовлев О.П., Сотникова А.Г. Конфокальная лазерная эндомикроскопия дыхательных путей - проблемы и перспективы. Клиническая практика. 2011; 4: 4-12.

[13]	Black P.N., Ching P.S., Beaumont B., Ranasinghe S., Taylor G., Merrilees M.J. Changes in elastic fibres in the small airways and alveoli in COPD. Eur. Respir. J. 2008; 31: 998-1004.

[14]	Bourg-Heckly G., Thiberville L., Vever-Bizet C., Vielerobe B. In vivo endoscopic autofluorescence microspectro-imaging of bronchi and alveoli. Proc. SPIE. 2008; 6851.

[15]	Fuchs F.S., Zirlik S., Hildner K., Frieser M., Ganslmayer M., Schwarz S. et al. Fluorescein-aided confocal laser endomicroscopy of the lung. Respiration. 2010; 81: 32-8.

[16]	Musani A., Sims M.W., Sareli C., Russell W., McLaren W., Delaney P. et al. A pilot study of the feasibility of confocal endomicroscopy for examination of the human airway. J. Bronchol. Intervent. Pulmonol. 2010; 17: 126-30.

[17]	Fuchs F.S., Zirlik S., Hildner K., Schubert J., Vieth M., Neurath M.F. Confocal laser endomicroscopy for diagnosing lung cancer in vivo. Eur. Respir. J. 2013; 41: 1401-8.

[18]	Aung H., DeAngelo B., Soldano J. et al. On alterations in the refractive index and scattering properties of biological tissue caused by histological processing. Proc. SPIE. 2013; 8592: 8.

[19]	Yserbyt J., Dooms C., Ninane V., Decramer M., Verleden G. Perspectives using probe-based confocal laser endomicroscopy of the respiratory tract. J. Swiss. Med. Wkly. 2013; 26: 14.