The treatment results of loco-regional recurrence of oral mucosa and the oropharynx squamous cell carcinoma

I. A Zaderenko; A. Yu Drobyshev; R. I Azizyan; S. B Alieva

doi:10.17816/onco40035

Russian Journal of Oncology ›› 2014, Vol. 19 ›› Issue (1) : 20 -25. DOI: 10.17816/onco40035

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The treatment results of loco-regional recurrence of oral mucosa and the oropharynx squamous cell carcinoma

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Abstract

The study included 314 patients with recurrent squamous cell carcinoma of the oral cavity and oropharynx after radical treatment. Patients were divided into groups depending on the timing - patients with early recurrence (n- 162), and late recurrence (n- 152), and depending on the type of treatment of recurrent tumors: conservative treatment group (n- 56 ), surgical (n- 235) and combined treatment group (n- 23). A comparative evaluation of the treatment effectiveness in these patients based on the results of treatment, survival rates, the frequency and severity of complications was performed. It was found that patients with late relapse have a better prognosis than patients with early relapse. Based on these data we can conclude that conservative therapy of recurrent tumors of the oral cavity if surgical treatment is impossible is effective, especially in cases of late recurrent tumors. Only the surgical or combined treatment may reach the five-year survival rate in patients with recurrent tumor, cancer of the oral cavity and oropharynx.

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squamous cell carcinoma / relapse / oral cavity / oropharynx

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I. A Zaderenko, A. Yu Drobyshev, R. I Azizyan, S. B Alieva. The treatment results of loco-regional recurrence of oral mucosa and the oropharynx squamous cell carcinoma. Russian Journal of Oncology, 2014, 19(1): 20-25 DOI:10.17816/onco40035

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