CLINICAL SEMIOTICS AND SURGICAL PREOPERATIVE DIAGNOSIS OF STAGE-I BREAST CANCER
I. V Kolyadina , D. V Komov , I. V Poddubnaya , T. Yu Danzanova , L. A Kostyakova , G. T Sinyukova , S. M Banov
Russian Journal of Oncology ›› 2013, Vol. 18 ›› Issue (4) : 17 -20.
CLINICAL SEMIOTICS AND SURGICAL PREOPERATIVE DIAGNOSIS OF STAGE-I BREAST CANCER
Screening tumors of breast are detected by instrumental methods of diagnosis, such as mammography (MG), ultrasonography (USG) and magnetic resonance imaging (MRI) only; typically have a size to 2.0 cm (T1) and need support (MG or USG control) at biopsy for morphological study. In the present study the clinical symptoms were analyzed using a large clinical data (1,347 patients with stage-I breast cancer), the rate of screening tumors and the possibility of pre-surgical biopsy of these tumors. The proportion of screening cancer, identified by instrumental methods of diagnosis was only 12.8%, which means the insufficient level of screening programs for all age groups women. Screening methods had the maximum diagnostic value in microcarcinomas (tumors less than 5 mm) which had no clinical symptoms and almost non-palpable. Young patients (<40 years) found breast cancer themselves and went to oncologist (more than 90% of cases; patients 50 years older - in 78% cases, p <0,05). Surgical biopsy with USG or MG control has improved the effectiveness of a biopsy from 74.4% (without instrumental control) to 93%; core-biopsy of tumors has helped to determinate of morphological diagnosis more exactly and plan treatment algorithm in these patients.
Screening breast cancer / clinical symptoms of breast cancer I-stage / fine-needle biopsy (FNAB) and corebiopsy with USG and MG control
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