HPV-ASSOCIATED OROPHARYNGEAL CANCER (A CLINICAL CASE)
A. R. Gevorkov , A. V. Boiko , A. V. Chernichenko , S. L. Daryalova , L. E. Zavalishina , A. A. Ryazantseva , V. V. Sokolov , A. A. Gladyshev
Russian Journal of Oncology ›› 2012, Vol. 17 ›› Issue (2) : 31 -34.
HPV-ASSOCIATED OROPHARYNGEAL CANCER (A CLINICAL CASE)
In recent years, human papillomavirus (HPV)-related oropharyngeal tumors have been more frequently detected in the world. Their proportion is 20 to 90% depending on the spread of smoking and the rate of alcohol consumption in the country conducting a study. On the other hand, the proportion of HPV-related squamous cell carcinoma of the oral and pharyngeal mucosae is higher in the countries loyal to sexual norms. According to recent data, HPV-related oropharyngeal cancer should be considered as an individual nosological entity characterized by a tendency to regional metastases generally in relatively small primary tumors and by a high sensitivity to chemotherapy and radiotherapy. The paper describes the experience in successfully treating a 56-year-old patient with locally advanced oropharyngeal cancer and HPV infection.
oropharyngeal cancer / chemoradiotherapy / human papillomavirus
| [1] |
Киселев Ф. Л. // Вопр. вирусол. — 1997. — Т. 42, № 6. — С. 248—251. |
| [2] |
Поляков П. Ю. Возможности управления тканевой радиочувствительностью в клинической онкологии: Автореф. дис.. д-ра мед. наук. — Обнинск, 2009. |
| [3] |
Applebaum K. M., Furniss C. S., Zeka A. et al. // J. Natl. Cancer Inst. — 2007. — Vol. 99. — P. 1801—1810. |
| [4] |
Benevolo M., Mottolese M., Marandino F. et al. // J. Clin. Cancer Res. — 2007. — Vol. 26, N 4. — P. 609—612. |
| [5] |
Dalianis T., Näsman A., Attner P. et al. // 25-th International papillomavirus conference. — Malmö, Sweden, 2009. — Abstr. O-17.04. |
| [6] |
HPV and other infectious agents in cancer: opportunities for prevention and public health / Eds H. Krueger et al. — New York: Oxford University Press, 2010. |
| [7] |
Jemal A., Siegel R., Ward E. et al. // Cancer J. Clin. — 2009. — Vol. 59, N 4. — P. 225—249. |
| [8] |
Kjaer S. K., Chackerian B., van den Brule A. J. et al. // Cancer Epidemiol., Biomarkers Prev. — 2001. — Vol. 10, N 2. — P. 101—106. |
| [9] |
Kreimer A. R., Clifford G. M., Boyle P., Franceschi S. // Cancer Epidemiol. Biomarkers Prev. — 2005. — Vol. 14. — P. 467—475. |
| [10] |
Nasman A., Attner P., Hammarstedt L. et al. // Int. J. Cancer. — 2009. — Vol. 125. — P. 362—366. |
| [11] |
Rintala M., Grenman S., Puranen M. et al. // J. Clin. Virol. — 2006. — Vol. 35, N 1. — P. 89—94. |
| [12] |
Scully C. // Br. Dent. J. — 2005. — Vol. 199, N 4. — P. 203—207. |
| [13] |
Shanthi M. // Lancet Oncol. — 2010. — Vol. 11. — P. 781—789. |
| [14] |
Shiboski C. H., Schmidt B. L., Jordan R. C. // Cancer. — 2005. — Vol. 103. — P. 1843—1849. |
| [15] |
zur Hausen H. // Proc. Assoc. Am. Physicians. — 1999. — Vol. 111, N 6. — P. 581—587. |
| [16] |
zur Hausen H. Infections causing human cancer. — Heidelberg: Wiley-VCH, 2006. |
Eco-Vector
/
| 〈 |
|
〉 |
PDF
