ROLE OF EPITHELIAL ANTIGEN BER-EP4 IN THE STUDY OF EXUDATES FROM SEROUS SACS

Abstract

Herzen Moscow Oncology Research Institute, Ministry of Health and Social Development of the Russian Federation Serous exudates with epithelial antigen BER-EP4 were studied using immunoperoxidase, immunofluorescence, and immunocytochemical methods and by a laser flow cytoflurometric technique. Up-to-date high-technologies make it possible to detect few tumor complexes in the exudate at early metastatic stages, which are undetectable by the routine cytological assay and to decrease the rate of hyperdiagnosis of a tumor process. The high efficiency and rapidity of immunofluorescence study of exudates are shown to establish the extent of the tumor process during urgent intraoperative studies.

Keywords

serous exudates / immunocytochemical assay / antigen BER-EP4

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