ORAL FUNGAL MICROFLORA IN PATIENTS WITH SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK DURING CHEMORADIOTHERAPY
L. I. Egorova , A. V. Maslennikova
Russian Journal of Oncology ›› 2012, Vol. 17 ›› Issue (1) : 11 -15.
ORAL FUNGAL MICROFLORA IN PATIENTS WITH SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK DURING CHEMORADIOTHERAPY
The oral fungal microflora was studied in 67 patients with squamous cell carcinoma of the head and neck and in people without cancer. In the patients with oropharyngeal tumors, Candida was shown to be encountered on the oral mucosa more frequently and in greater quantities than in the persons without cancer. Chemoradiotherapy causes a statistically significant increase in the Candida colonization index and changes in the qualitative composition of the oral fungal microflora. The coadministration of Candida solution and immunal can normalize the microbial landscape.
squamous cell carcinoma of the head and neck / chemoradiotherapy / mucositis / prevention / Candida genus fungi / candidiasis
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