Methodological aspects of the fluorescence diagnosis of malignancies by using alasens
E V Filonenko , A B Grishaeva , E V Filonenko , A B Grishayeva
Russian Journal of Oncology ›› 2011, Vol. 16 ›› Issue (5) : 30 -33.
Methodological aspects of the fluorescence diagnosis of malignancies by using alasens
The paper presents the results of using the kinetics of tissue distribution of alasens-induced protoporphyrin IX (PPIX) in patients with tumors of various sites during local and systemic administrations of alasens. The time to achieve the maximum intensity of alasens-induced PPIX fluorescence in tumor and the fluorescence ratio "tumor/norm value", as well as the level of alasens-induced PPIX fluorescence are shown to depend on the route of alasens administration. Procedures for fluorescence diagnosis using alasens are clarified in accordance with the findings.
5-aminolevulinic acid / alasens-induced protoporphyrin IX / fluorescence diagnosis
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