Experimental rationale for the duration of radiofrequency thermal ablation for bone tumor involvement
V V Teplyakov , G A Frank , A V Bukharov , G D Efremov , V Yu Karpenko , I V Myslivtsev , V V Teplyakov , G A Frank , A V Bukharov , G D Efremov , V Yu Karpenko , I V Myslivtsev
Russian Journal of Oncology ›› 2011, Vol. 16 ›› Issue (4) : 37 -39.
Experimental rationale for the duration of radiofrequency thermal ablation for bone tumor involvement
Experimental animals (sheep) underwent radiofrequency thermal ablation (RFTA) of iliac bones (spongy bones) for 2, 4, 6, 8, 10, and 12 minutes, followed by a histological study. There was bone necrosis in all the radiofrequency wave exposure periods (2 to 12 minutes), the fragments of osseous structures in the RFTA periods of 10 to 12 minutes showed obvious signs of coagulation necrosis with carbonization. The radius of bone necrosis varied from 15 to 20 mm under 2-6-min hyperthermia and 8-12-min thermal ablation. The findings show that 4-6-min RFTA exposure was sufficient for malignancies not exceeding 3 cm in diameter and the time of hyperthermia for bone metastases must be 8-10 minutes.
radiofrequency thermal ablation / bone tumors
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