Neoad\"yuvantnaya khimioterapiya pri lechenii zlokachestvennykh novoobrazovaniy pryamoy kishki
V V Dvornichenko , A V Shevchuk , A V Shelekhov , D M Ponomarenko , E V Snetkov
Russian Journal of Oncology ›› 2010, Vol. 15 ›› Issue (4) : 37 -39.
Neoad\"yuvantnaya khimioterapiya pri lechenii zlokachestvennykh novoobrazovaniy pryamoy kishki
The authors propose a rectal cancer treatment program that includes preoperative chemotherapy in 14 men and 6 women.. Nonadjuvant chemotherapy was performed in combination with radiotherapy in the preoperative specialized treatment stage. Stage 1 treatment comprised classical fractionation gamma-teletherapy once used on the first day of RIFL chemotherapy was made. Surgery was performed 3 or 4 weeks after chemoradiotherapy. Pathomorphological study of intraoperative specimens showed grades I-II and III-IV pathomorphism in 4 and 16 patients, respectively. The efficiency of the treatment permits a combination of preoperative chemotherapy and classical fractionation radiotherapy use in patients with locally advanced rectal cancer.
rectal malignancies / nonadjuvant chemotherapy
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