LUChEVAYa TERAPIYa I POLIKhIMIOTERAPIYa V LEChENII MESTNO-RASPROSTRANENNYKh FORM RAKA ShEYKI MATKI

Abstract

The results of treatment were retrospectively analyzed in 286 patients aged 20-79 years with locally advanced cancer of the cervix uteri; of them 178 patients received concomitant radiation treatment (a control group) and 108 had concomitant radiation treatment and polychemotherapy included into a cisplatin treatment regimen (a study group). Analysis of treatment results indicated that in the study group there was a rise in the rate of a systemic antitumor effect up to 85.2%, a decrease in that of local recurrences, and a 10% increase in three-year survival rates.

Keywords

locally advanced cancer of the cervix uteri / radiation therapy / polychemotherapy / platinum preparations

References

[1] Клиническая онкогинекология: Руководство для врачей / Под ред. В. П. Козаченко. - М., 2005.

[2] Онкогинекология: Руководство для врачей / Под ред. З. Ш. Гилязутдиновой, М. К. Михайлова. - М., 2000.

[3] Практическая онкогинекология: избранные лекции / Под ред. А. Ф. Урманчиевой и др. - СПб., 2008.

[4] Чиссов В. И., Старинский В. В., Ковалев Б. П. и др. // Казан. мед. журн. - 2000. - № 4. - С. 241-249.

[5] Friendlander V. L., Atkinson K., Coppleson M. et al. // Gynecol. Oncol. - 1994. - Vol. 19. - P. 1.

[6] Keys H. M., Bundy B. N., Stehman F. B. et al. // N. Engl. J. Med. - 1999. - Vol. 340. - P. 1154-1161.

[7] Neoadjuvant Chemotherapy for Cervical Cancer Meta-analysis Collaboration (NACCCMA) // Cochrane Database Syst. Rev. - 2004. - N 1. - CD001774.

[8] Rose P. G., Bundy B. N., Watkins E. B. et al. // N. Engl. J. Med. - 1999. - Vol. 340. - P. 1144-1153.

[9] Sardi J., Sananen C., Giaroli A. et al. // Int. J. Gynecol. Cancer. - 1998. - Vol. 8. - P. 441-450.

[10] Thomas G. M. // N. Engl. J. Med. - 1999. - Vol. 340. - P. 1175-1178.

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