Gialiniziruyushchaya trabekulyarnaya opukhol' shchitovidnoy zhelezy

P G Mal'kov , M A Morozova , V N Grinevich , A Yu Abrosimov , A M Minasyan

Russian Journal of Oncology ›› 2010, Vol. 15 ›› Issue (1) : 46 -48.

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Russian Journal of Oncology ›› 2010, Vol. 15 ›› Issue (1) : 46 -48. DOI: 10.17816/onco39744
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Gialiniziruyushchaya trabekulyarnaya opukhol' shchitovidnoy zhelezy

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Abstract

The paper describes a case of thyroid hyalinizing trabecular tumor in a 55-year-old woman. Cytological examination of her fine-needle biopsy specimen showed separately lying tumor cells with intracellular cytoplasmic inclusions. Its cytological study determined the trabeculoalveolar structures formed by tumor cells, the intercellular space exhibited a homogenous eosinophilic matter that yielded a positive Schick's test, laminated calcinates that mimick psammoma bodies. Immunophenotyping of the neoplasm revealed a positive reaction with antibodies to thyroglobulin, a negative reaction to galectin-3 and cytokeratin-19, and membrane Ki-67 expression, which suggests the low malignancy potential.

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thyroid / hyalinizing trabecular tumor

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P G Mal'kov, M A Morozova, V N Grinevich, A Yu Abrosimov, A M Minasyan. Gialiniziruyushchaya trabekulyarnaya opukhol' shchitovidnoy zhelezy. Russian Journal of Oncology, 2010, 15(1): 46-48 DOI:10.17816/onco39744

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