Cytokines and monoamines in pathogenesis of multiple sclerosis

B. T. Khaidarov , V. Р. Kuznetsov , М. N. Zakharova , D. L. Belyaev , V. P. Barhatova , О. S. Brusov , А. А. Babayants , L. S. Askarova , А. D. Konysova , I. A. Zavalishin

Neurology Bulletin ›› 1996, Vol. XXVIII ›› Issue (3-4) : 5 -9.

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Neurology Bulletin ›› 1996, Vol. XXVIII ›› Issue (3-4) :5 -9. DOI: 10.17816/nb79635
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Cytokines and monoamines in pathogenesis of multiple sclerosis

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The article presents the results of research of cytokines (α- and ß-interferons and tumor necrosis factor-а) and monoamines (adrenalin, noradrenalin, dopamin, serotonin) in blood and cerebrospinal fluid in 151 patients with multiple sclerosis. The correlation between immune, biochemical changes and clinical activity and course of disease were revealed. The immunocorrection with α-interferon is recommended.

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Neurological archive of Bekhterev

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B. T. Khaidarov, V. Р. Kuznetsov, М. N. Zakharova, D. L. Belyaev, V. P. Barhatova, О. S. Brusov, А. А. Babayants, L. S. Askarova, А. D. Konysova, I. A. Zavalishin. Cytokines and monoamines in pathogenesis of multiple sclerosis. Neurology Bulletin, 1996, XXVIII(3-4): 5-9 DOI:10.17816/nb79635

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References

[1]

Зимина И.В., Лопухин Ю.М., Арион В.Я. Кожа как иммунный орган: Клеточные элементы и цитокины // Иммунология.—1994.—№ 1.—С.8—13.

[2]

Benveniste E.N. Inflammatory cytokines within central nervous system: sources, function and mechanism of action // An. J. Physiol.—1992—Vol.263.-P. 1—16.

[3]

Benvenuto R., Parolli M., Buttinelle C. Tumor necrosis factor alpha and interferon-gamma synthesis by cerebrospinal fluidderived T-cell clones in multiple sclerosis // Ann. N. J. Acad. Sсi.—1992,—Vol.690.—P.341—346.

[4]

Chelmicka-Schorr E. et. al. Chemical sympathectomy augments the severity of experimental allergic encephalomyelids // J. Neuroimmunol.—1988.—Vol. 17,—P.347—350.

[5]

Chelmicka-Schorr E., Arnason B.G. Nervous system — Immune system interactions and their role in multiple sclerosis // Annals of neurol.—1994.—Vol.36.—P.29—33.

[6]

Ellison J.W. et al. Design Strategies in Multiple Sclerosis Clinical Trials // Annals of neurology.—1994.—Vol.36.— P.108—113.

[7]

Jacobs L., Johnson K.P. A brief history of tne use of interferons as treatment of multiple sclerosis // Arch. Neurol.—

[8]

.—Vol. 51—P.1245—1252.

[9]

Hartung H.P. et al. Circulating adhesion molecules and inflammatory, mediators in demyelination // Neurology.—

[10]

—Vol.45.—P.22—32.

[11]

Heyes M.P. Lackner A. AIDS-dementia and excitotoxicity // J. Neurochem.—1992— Vol.55.—P.338—341.

[12]

Ignarro L.J. Nitric Oxide // Hypotension.—1990.— Vol. 16.—P.477—483.

[13]

Karaszevski J.W., Reder A., Anlas B., Arnason B. Increased high affinity beta-adrenergic receptor densities and cyclic AMP responses of CD8 cells in multiple sclerosis // J. Neuroimmunol.—1993.—Vol.43.—P. 1—8.

[14]

Medenda R.F. et al. Plasmapheresis combined with interferon: an effective therapy for multiple sclerosis // J. Clin.—Apheresis.—1994— Vol.9.—P.222—227.

[15]

Me Carthy K.D., Salm A. Astroglial receptors and their regulation of intermediate filament protein phosphorylation // Glial and Cell Receptor.—CD. H.Kimetberg; New York: Raven Press.—1989.—P.1—23.

[16]

Raine C.S. The Immunology of the multiple sclerosis // Annals of Neurol.—1994.—Vol.36.—P.61—73.

[17]

Ransohoff R.M., Estes M.L. Astrocyte expression of major histocompatibility complete gene products in multiple sclerosis brain tissue obtained by stereotactic biopsy // Arch. Neurol.—1991.—Vol.48.-P. 1244—1246.

[18]

Werner H. et al. Interaction between lymphocytes and neurotransmitters // Annals of the New York Academy of Sciences—1988,—Vol.496.—P.312— 316.

[19]

Whitaker J.N. Rationale for immunotherapy in multiple sclerosis // Annals of Neurol.—1994.—Vol.36.— P. 103—108.

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Khaidarov B.T., Kuznetsov V.Р., Zakharova М.N., Belyaev D.L., Barhatova V.P., Brusov О.S., Babayants А.А., Askarova L.S., Konysova А.D., Zavalishin I.A.

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