A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia (Proc. Natl. Acad. Sci. USA. — 1999. — Nov. 9. — Vol. 96. — P. 13496 — 13500: англ.)
J. Yrjanheikki , T. Tikka , R. Keinanen , G. Goldsteins , P. H. Chan , J. Koistinaho
Neurology Bulletin ›› 2000, Vol. XXXII ›› Issue (3-4) : 76 -76.
A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia (Proc. Natl. Acad. Sci. USA. — 1999. — Nov. 9. — Vol. 96. — P. 13496 — 13500: англ.)
One of the reasons for the insufficient effectiveness of treatment of acute ischemic stroke may be secondary inflammation of the brain tissue, which, according to the results of modern studies, significantly worsens the consequences and outcome of the disease.
Yrjanheikki J., Tikka T., Keinanen R., Goldsteins G., Chan P.H., Koistinaho J.
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