When defining each nervous disease, as a separate nosological unit, modern neuropathology lays in the basis of three main principles: anatomical-physiological, pathological-anatomical and ethiological. On the basis of the first principle, the neuropathologist, using the facts of normal anatomy and physiology of the nervous system, determines in the clinical picture of the disease, the evasion in the manifestation of the activity of individual nervous systems, nervous units - neurons. Determining which systems and which parts of them are affected, he sets the topical diagnosis of the disease. Based on the data of the pathological anatomy, the neuropathologist determines the nature of the lesion underlying the disease, and finally determines the cause that caused this disease, which caused the rapidity or slowness of its development, using the data of toxicology and toxicology in acute cases. But in spite of the successes of neuropathology, there are many diseases where all three principles cannot be strictly followed, since they represent a lot more controversial. These diseases are presented as a symptom complex, in the basis of which there may be lesions, extremely diverse in their localization, in the nature of the pathological-anatomical process and in ethiology. To the number of such kind of diseases belongs the disease, known under the name of acute ascending paralysis of Landry.