Cognitive impairment in patients on hemodialysis

Alexey E. Khrulev; Svetlana F. Studyanikova; Svetlana V. Langraf; Roman V. Sadyrin; Vera N. Grigoryeva

doi:10.17816/nb15659

Neurology Bulletin ›› 2019, Vol. LI ›› Issue (2) : 36 -40. DOI: 10.17816/nb15659

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Cognitive impairment in patients on hemodialysis

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Abstract

The aim of research was to study cognitive impairment (CI) in patients on hemodialysis (HD): 63 people (25 men and 38 women) aged 38 to 72 years (mean age 54. 2±11. 1 years). The main group consisted of 43 people on HD. The control group consisted of 20 relatively healthy individuals without kidney disease. A clinical neurological examination, MoCA and Mini-Cog tests were conducted. It was found that CI are much more common in patients on HD (according to MoCA, 81. 4%; Mini-Cog, 34. 9%). The inverse dependence of the cognitive status on the duration of dialysis patients was demonstrated (r=-0. 27, p≤0. 05). A weak correlation between MoCA test and the adequacy of the dialysis dose (kt/V index) was detected. The structure of CI in HD patients was dominated by memory impairment, visual-constructive disorders, changes in the executive skills and fluency of speech.

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cognitive impairment / chronic kidney disease / hemodialysis / MoCA / Mini-Cog

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Alexey E. Khrulev, Svetlana F. Studyanikova, Svetlana V. Langraf, Roman V. Sadyrin, Vera N. Grigoryeva. Cognitive impairment in patients on hemodialysis. Neurology Bulletin, 2019, LI(2): 36-40 DOI:10.17816/nb15659

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