Zingerle. To the pathological anatomy of dementia praecox. Zur pathologischen Anatomie der dementia praecox. Monatsch. f. Psych. and Neurology. bd. XXVII, S. 285 (1910)
Vitaly N. Likhnitsky
Neurology Bulletin ›› 1910, Vol. XVII ›› Issue (4) : 870 -871.
The author describes in detail the changes in the central nervous system that he found in the case of dementia praecox catatonica. Comparing the changes found by him with those that were previously described by various researchers, Zingerle comes to the conclusion that with dementia praecox we are dealing with a diffuse process that captures all elements of the central nervous system. The nerve cells and fibers of the gray matter of the brain suffer most in this case; the elements of the neuroglia also turn out to be changed, and only a part of these changes can be considered a reaction to the destruction of the nervous tissue; so, in the circumference of large and small vessels of the white matter of the brain, where it is not possible to detect the degeneration of nerve fibers, one can often find a clearly expressed growth of neuroglia.
A characteristic feature of dementia praecox, in contrast to progressive paralysis, is the absence of any significant changes in the vessels of the brain or its membranes.
Likhnitsky V.N.
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