GASOTRANSMITTERS IN THE REGULATION OF THE FUNCTIONS OF THE INTRAORGANIC BLOOD VESSELS OF THE UTERUS

Abstract

Despite the fact that the intraorganic circulatory bed is the main element providing adequate blood supply to organ structures, its structure, functions and regulatory mechanisms in the uterus are largely unknown. The review presents the literature data and own materials on the localization and distribution of gasotransmitters in the intraorganic vessels of the uterus. The cellular and molecular mechanisms of the participation of NO, CO and H2S in the regulation of the function of these vessels are rewieved. On the one hand, these materials emphasize the importance of these signaling molecules in the regulation of contractility of the smooth muscles of the blood vessels and capillary permeability, on the other hand, point out the need for further studies of the role of gasotransmitters in the general system of uterine hemodynamic regulation.

Keywords

uterus / intraorganic vessels / nitric oxide / carbon monoxide / hydrogen sulfide

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Chertok V.M., Khramova I.A., Kotsyuba A.Y.