FORMATION OF OSSIFICATION NUCLEUS IN THE FEMORAL HEAD IN HAMSTERS EXPOSED TO LASER RADIATION

Abstract

The purpose of the study was to detect the relation between the formation of ossification nucleus in the epiphysis and the ingrowth of vessels into it, using laser radiation of femoral heads. The study was performed in 30 golden hamsters, 20 of them starting at 10 days after birth were exposed to daily irradiation of the right hip joint(during 3-80 days). The left joint was used as control. The radiation was performed with «Agnis» laser device (radiation power - 2 mW, impulse frequency - 2500 Hz, exposure duration - 8 min, optical fiber diameter - 4 mm). Femoral bones of experimental and control animals were histologically studied at days 13 till 90. Laser radiation was found could delay vessel growth from diaphysis into epiphysis for up to 13 days, and the beginning of ossification nucleus formation in the femoral head - for up to 5 days. This suggests the direct relation of the development of bone ossification nucleus in the epiphysis and growing of vessels into its cartilage, since no other factors retarding the vessel growth and formation of bone nucleus were used.

Keywords

bone / development / epiphysis ossification / vessels / laser

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