THE REGULARITIES OF DEVELOPMENT AND FORMATION OF THE MUCOSAL IMMUNE SYSTEM OF THE SMALL INTESTINE
A Yu YULDASHEV , Z A KAKHAROV , M A YULDASHEV
Morphology ›› 2008, Vol. 134 ›› Issue (6) : 42 -46.
THE REGULARITIES OF DEVELOPMENT AND FORMATION OF THE MUCOSAL IMMUNE SYSTEM OF THE SMALL INTESTINE
Моrphologic and morphometric characteristics of the grouped lymphoid nodules (Peyer's patches) and of the small intestine lamina propria were studied in rats at the 19 prenatal and 1, 7, 14, 21, 90 postnatal days. The development of these structures was found to be heterochronic and fragmentary. The development of the individual components of the mucosal immune system was interrelated. The integration of the afferent and efferent limbs of the mucosal immune system with the processes of digestion and absorption, is regarded as its adaptation to the peculiarities of postnatal development of mammals and as the property of the functional system, maintaining the homeostasis of the internal milieu of the organism.
grouped lymphoid nodules (Peyer's patch) / mucosal immune system / small intestine / rat
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