COMPARATIVE CHARACTERISTIC OF MORPHOMETRIC PARAMETERS OF GERMINAL CENTERS IN THE AGGREGATED LYMPHOID NODULES OF THE SMALL INTESTINE AND MESENTERIC LYMPH NODES FOLLOWING ACUTE EMOTIONAL STRESS

E A Ivanova; Ye A Ivanova

doi:10.17816/morph.399575

Morphology ›› 2011, Vol. 140 ›› Issue (6) : 64 -68. DOI: 10.17816/morph.399575

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COMPARATIVE CHARACTERISTIC OF MORPHOMETRIC PARAMETERS OF GERMINAL CENTERS IN THE AGGREGATED LYMPHOID NODULES OF THE SMALL INTESTINE AND MESENTERIC LYMPH NODES FOLLOWING ACUTE EMOTIONAL STRESS

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Abstract

Under physiological conditions, the germinal center (GC) area of aggregated lymphoid nodules of the small intestine in adult male Wistar rats was greater than that of the similar structures in the mesenteric lymph nodes. Moreover, these differences were more pronounced in a group of stress-resistant rats as compared to stress-prone animals. The exposure to acute emotional stress (immobilization in plexiglas boxes for 1 hour with the irritation of the back area with the electric current) reduced GC size. Restoration of the morphometric parameters studied in the group of stress-resistant rats was completed at an earlier date (by Day 3 after exposure to stress), while in susceptible animals it took place by Day 7. By Day 14 after an acute emotional stress, GC size in a group of stress-resistant rats were similar to those in control group, while in susceptible animals they were lower than the baseline values, indicating that the depletion of the functional capacities of lymphoid tissue in this group of animals.

Keywords

aggregated lymphoid nodules / mesenteric lymph nodes / germinal centers / acute emotional stress / Wistar rats

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E A Ivanova, Ye A Ivanova. COMPARATIVE CHARACTERISTIC OF MORPHOMETRIC PARAMETERS OF GERMINAL CENTERS IN THE AGGREGATED LYMPHOID NODULES OF THE SMALL INTESTINE AND MESENTERIC LYMPH NODES FOLLOWING ACUTE EMOTIONAL STRESS. Morphology, 2011, 140(6): 64-68 DOI:10.17816/morph.399575

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References

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[1]	Автандилов Г.Г. Медицинская морфометрия. М., Медицина, 1990.

[2]	Аминова Г.Г. Структура лимфоидных узелков и их систематизация. В кн.: Научная конференция «Актуальные вопросы морфогенеза в норме и патологии»: Сборник научных трудов. М., МДВ, 2010, с. 6-9.

[3]	Белоцкий С.М. и Авталион Р.Р. Воспаление. Мобилизация клеток и клинические эффекты. М., БИНОМ, 2008.

[4]	Бузунов А.Ф. Формирование соматических последствий адаптационного синдрома. Цена цивилизации. М., Практическая медицина, 2010.

[5]	Виноградов В.В. Стресс и патология. Минск, Белорус. наука, 2007.

[6]	Горячкина Л.А. и Кашкин К.А. Клиническая аллергология и иммунология: руководство для практикующих врачей. М., Миклош, 2009.

[7]	Коплик Е.В. Метод определения критерия устойчивости крыс к эмоциональному стрессу. Вестн. новых мед. технологий, 2002, т. 1Х, № 1, с. 16-18.

[8]	Лебедев К.А. и Понякина И.Д. Иммунология образраспознающих рецепторов (интегральная иммунология). М., Книжный дом «ЛИБРОКОМ», 2009.

[9]	Никулин Б.А. Оценка и коррекция иммунного статуса. М., ГЭОТАР-Медиа, 2007.

[10]	Райт Д. Морфологическая диагностика патологии лимфатических узлов. М., Мед. лит., 2008.

[11]	Сапин М.Р. и Никитюк Д.Б. Иммунная система, стресс и иммунодефицит. М., АПП «Джангар», 2004.

[12]	Судаков К.В. и Умрюхин П.Е. Системные основы эмоционального стресса. М., ГЭОТАР-Медиа, 2010.

[13]	Dhabhar F.S. Stress - induced augmentation of immune function - the role of stress hormones, leukocyte trafficking, and cytokines. Brain Behav. Immun., 2002, v. 16, № 6, p. 785-798.

[14]	Dommett R., Zilbauer M., George J.T. and Bajaj-Elliott M. Innate immune defense in the human gastrointestinal tract. Molec. immunol., 2005, v. 42, № 8, p. 903-912.

[15]	Necela B.M. and Cidlowski J.A. Mechanisms of glucocorticoid receptor action in non inflammatory and inflammatory cells. Proc. Amer. Thorac. Soc., 2004, v. 1, p. 239-246.