TISSUE REACTIONS OF THE LARYNGEAL MUCOUS MEMBRANE AND ITS REGULATORY STRUCTURES IN EXPERIMENTAL CHRONIC LARYNGITIS

F M Khamidova; S A Blinova; F M Khamidova; S A Blinova

doi:10.17816/morph.399386

Morphology ›› 2010, Vol. 138 ›› Issue (5) : 40 -43. DOI: 10.17816/morph.399386

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TISSUE REACTIONS OF THE LARYNGEAL MUCOUS MEMBRANE AND ITS REGULATORY STRUCTURES IN EXPERIMENTAL CHRONIC LARYNGITIS

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Abstract

Experimental chronic laryngitis (ECL) was induced in 34 adult male rabbits by placement of fosta nylon thread into their trachea. Changes in the laryngeal mucous membrane in ECL were studied at days 30-90 using histological, histochemical and morphometric methods. ECL resulted in the thickening of both the epithelium and lamina propria of the laryngeal mucous membrane. In the ECL dynamics, the thickness of stratified squamous epithelium was increased insignificantly, however, it demonstrated the stimulation of the focal hyperplastic processes. Lamina propria, underlying this epithelium, was found to become thicker throughout the whole experiment (days 30-90). At the same time, progressive growth of the thickness of both pseudostratified ciliated epithelium and the lamina propria beneath was observed. This was accompanied by the hyperplasia of laryngeal endocrine cells and the increase of their secretory activity.

Keywords

larynx / mucous membrane / endocrine cells / experimental laryngitis

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F M Khamidova, S A Blinova, F M Khamidova, S A Blinova. TISSUE REACTIONS OF THE LARYNGEAL MUCOUS MEMBRANE AND ITS REGULATORY STRUCTURES IN EXPERIMENTAL CHRONIC LARYNGITIS. Morphology, 2010, 138(5): 40-43 DOI:10.17816/morph.399386

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References

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[1]	Блинова С.А.Нейроэндокринная система органов дыхания в норме и в условиях патологии. Пробл. биол. и мед., 2000, № 1, с. 22-24.

[2]	Бубнова Н.И. Хронические неспецифические воспалительные заболевания легких у детей. В кн.: Клеточная биология легких в норме и при патологии. М., Медицина, 2000, с. 351-357.

[3]	Дайняк Л.Б. Особые формы острых и хронических ларингитов. Вестн. оторинолар., 1997, № 7, с. 45-49.

[4]	Райхлин Н.Т., Кветной И.М., Цыб А.Ф. и Гарбузов П.И. АPUDсистема и опухолевый рост. В кн.: АPUD-система (общепатологические и онкологические аспекты). Ч. 2. Обнинск, Изд-во НИИМР РАМН, 1993, с. 116-125.

[5]	Швалев В.Н. и Жучкова Н.Н. Простой способ выявления адренергических нервных структур в тканях человека и животных с применением раствора глиоксиловой кислоты. Арх. анат., 1979, т. 76, вып. 6, с. 114-116.

[6]	Albegger K., Hauser-Kronberger C.E., Saria A. et al. Regulatory peptides and general neuroendocrine markers in human nasal mucosa, soft palate and larynx. Acta Otolaryngol., 1991, v. 111, № 2, p. 373-378.

[7]	Birchall M.A., Bailei M., Gutowska-Owsiak D. et al. Immunological response of the laryngeal mucosa to extra esophageal reflux. Ann. Otol. Rhinol. Laryngol., 2008, v. 117, № 12, p. 891-895.

[8]	Gale N., Zidar N., Fischinger J. and Kambic V. Clinical applicability of the Ljubljana classification of epithelial hyperplastic laryngeal lesions. Clin. Otolaryngol. Allied. Sci., 2000, v. 25, № 3, p. 227-232.

[9]	Peace C., Tobia-Gallelli F. and Toncini C. APUD cells of the larynx. Acta Otolaryngol., 1984, v. 98, № 1-2, p. 158-162.

[10]	Yamamoto Y., Atoli Y. and Suzuki Y. Calbidin D28k-immunoreactive afferent nerve endings in the laryngeal mucosa. Anat. Rec., 2000, v. 259, № 3, p. 237-247.