THE DEGREE OF APOPTOSIS EXPRESSION IN THE NUCLEI OF PLACENTAL VILLI SYNCYTIOTROPHOBLAST IN HERPES VIRUSINFECTION

M T Lutsenko; I A Andrievskaya; M T Lutsenko; I A Andriyevskaya

doi:10.17816/morph.399074

Morphology ›› 2009, Vol. 135 ›› Issue (1) : 46 -48. DOI: 10.17816/morph.399074

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THE DEGREE OF APOPTOSIS EXPRESSION IN THE NUCLEI OF PLACENTAL VILLI SYNCYTIOTROPHOBLAST IN HERPES VIRUSINFECTION

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Abstract

Using light, electron microscopy and immunocytochemistry (ISEL-method) the nuclei of placental villi syncytiotrophoblast were studied in puerperas, who had the outburst of Herpes virus infection in the second half of their pregnancy (antibody titre 1:6400 - 1:12800). The results obtained have shown that Herpes virus invasion into the placental barrier caused the changes of metabolism in syncytiotrophoblast nuclei, that lead to the appearance of signs of apoptosis. The number of nuclei demonstrating apoptotic changes was increased in proportion with the increase of the severity of Herpes virus infection

Keywords

placenta / syncytiotrophoblast / nucleus / apoptosis / Herpes virus infection

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M T Lutsenko, I A Andrievskaya, M T Lutsenko, I A Andriyevskaya. THE DEGREE OF APOPTOSIS EXPRESSION IN THE NUCLEI OF PLACENTAL VILLI SYNCYTIOTROPHOBLAST IN HERPES VIRUSINFECTION. Morphology, 2009, 135(1): 46-48 DOI:10.17816/morph.399074

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