Parasympathetic innervation of proximal parts of the colon in cat

Abstract

The localization and morphometric features of efferent para-sympathetic neurons of the vagus dorsal motor nucleus and of the spinal sacral parasympathetic nucleus innervatingthe area of ileocaecal sphincter, ascending and transverse colon, were investigated. In urethane anaesthetized cats, the solution of horseradish peroxidase was injected under the serosa of the indicated areas of colon. In 48 hours animals were transcardially perfused with a fixative solution. Sections of the medulla oblongata and the sacral spinal cord were stained using Mezulam's technique (1978). It was shown that all the areas of the colon studied received parasympathetic innervation from the neurons of the ventrolateral part of the vagus dorsal motor nucleus, which were uniform according to their morphometric characteristics. The number of neurons in this group, sending their axons to the ileocaecal area, was greater than the number of neurons, innervating ascending colon. Second group of neurons, that was represented by smaller cells, was located in the same part of the nucleus and innervated transverse colon. Transverse colon had an additional parasympathetic supply from the neurons of the spinal sacral parasympathetic nucleus.

Keywords

colon / parasympathetic innervation / cat / horseradish peroxidase

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