STRUCTURE-FUNCTIONAL CHANGES IN RAT PANCREAS AFTER GLUCOSE INJECTION
V F Ivanova , A A Puzyrev , V F Ivanova , A A Puzyryov
Morphology ›› 2006, Vol. 129 ›› Issue (1) : 67 -71.
STRUCTURE-FUNCTIONAL CHANGES IN RAT PANCREAS AFTER GLUCOSE INJECTION
Electron microscopic method was used to study the effect of hyperglycemia on the pancreas of albino rats (n=20) after intraperitoneal administration of 40% glucose solution (daily, for 5 days). The data obtained suggest that repeated administration of glucose was accompanied by marked changes in the structure B-endocrinocytes, indicative of the increased secretion of the insulin. This resulted in the appearance of new small pancreatic islets, that consisted of B-endocrinocytes and acino-insular cells. Most frequently acinar-insular cells were located at the periphery of newly formed islets. The latter often had a symplast-type structural organization.
pancreatic islets / B-endocrinocytes / acino-insular cells / ultrastructure / glucose
Eco-Vector
/
| 〈 |
|
〉 |
PDF
