APPEARANCE OF STELLATE SMOOTH MUSCLE CELLS IN THE RAT BRAIN AFTER TRANSITORY FOCAL ISCHEMIA

D. E. Korzhevskiy; O. V. Kirik; T. D. Vlasov

doi:10.17816/morph.398637

Morphology ›› 2013, Vol. 143 ›› Issue (1) : 073 -075. DOI: 10.17816/morph.398637

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APPEARANCE OF STELLATE SMOOTH MUSCLE CELLS IN THE RAT BRAIN AFTER TRANSITORY FOCAL ISCHEMIA

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Abstract

One of the poorly studied problems of the pathogenesis of the brain ischemic damage is the early reorganization of blood vessels in the zone of the transitory ischemia. The aim of the present study was to investigate the structural organization and cytochemical characteristics of smooth muscle cells (SMC) in the wall of the intracerebral blood vessels in 16 Wistar rats during the early postischemic period (48 hrs after a 30 minute-long ischemia). Examination of the lesioned hemisphere revealed the stellate cells, demonstrating positive reaction to alpha-smooth muscle actin, which seem to be a special population of structurally modified SMC, uncharacteristic to the intact brain of control animals (n=5). The functional role of these cells remains to be elucidated.

Keywords

brain / ischemia / smooth muscle cells / alpha-actin / brain / ischemia / smooth muscle cells / alpha-actin

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D. E. Korzhevskiy, O. V. Kirik, T. D. Vlasov. APPEARANCE OF STELLATE SMOOTH MUSCLE CELLS IN THE RAT BRAIN AFTER TRANSITORY FOCAL ISCHEMIA. Morphology, 2013, 143(1): 073-075 DOI:10.17816/morph.398637

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