OSTEOPLASTIC EFFECTIVENESS OF MINERALIZED BONE MATRIX

Yu. M. Irianov

Morphology ›› 2013, Vol. 143 ›› Issue (1) : 063 -068.

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Morphology ›› 2013, Vol. 143 ›› Issue (1) : 063 -068. DOI: 10.17816/morph.398631
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OSTEOPLASTIC EFFECTIVENESS OF MINERALIZED BONE MATRIX

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Abstract

In the experiment conducted on 50 Wistar rats, the peculiarities of the reparative osteogenesis were studied using scanning electron microscopy, x-ray electron-probe microanalysis and histological techniques. Granulated mineralized bone matrix (MBM) obtained without thermal and demineralizing treatment, was implanted into the tibial defect. MBM was found to possess marked osteoinductive and osteoconductive properties. It induced a prolonged activation of reparative osteogenesis after the implantation, as well as deep bone tissue ingrowth into the implant, acceleration of organotypic remodeling of regenerated bone, intense angiogenesis and early restoration of the damaged bone.

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bone defect / implantation / mineralized bone matrix

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Yu. M. Irianov. OSTEOPLASTIC EFFECTIVENESS OF MINERALIZED BONE MATRIX. Morphology, 2013, 143(1): 063-068 DOI:10.17816/morph.398631

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