STRUCTURAL CHANGES IN THE SENSORY GANGLIA OF THE SPINAL NERVES AFTER REPEATED MAGNETIC STIMULATION ON THE MODEL OF ISCHEMIC MYELOPATHY

L. S. Onishchenko , D. A. Iskra

Morphology ›› 2013, Vol. 143 ›› Issue (2) : 024 -029.

PDF
Morphology ›› 2013, Vol. 143 ›› Issue (2) : 024 -029. DOI: 10.17816/morph.398606
Articles
research-article

STRUCTURAL CHANGES IN THE SENSORY GANGLIA OF THE SPINAL NERVES AFTER REPEATED MAGNETIC STIMULATION ON THE MODEL OF ISCHEMIC MYELOPATHY

Author information +
History +
PDF

Abstract

The aim of this study was to examine the association of morphological changes in the sensory ganglia of the spinal nerves (SGSN) with the cilinical symptomatology in rats with the experimentally induced ischemic myelopathy (IM), untreated or treated with repeated magnetic stimulation (RMS). The efficacy and mechanisms of RMS action on SGSN were studied by electron microscopy in 16 rats with IM. According to the results of treatment, in SGSN both at a distance from the damaged area (lumbar SGSN) and close to it (cervical SGSN) the morphological signs of regenerative-reparative processes were found in the cells and nerve fibers (restoration of the organelle structure in the cytoplasm o0f neurons and neurolemmocytes, the increase in the number of he latter and fiber remyelination). The expression of the structural changes correlated with the degree of functional recovery.

Keywords

sensory ganglia of the spinal nerves / ischemic myelopathy / repeated magnetic stimulation / electron microscopy

Cite this article

Download citation ▾
L. S. Onishchenko, D. A. Iskra. STRUCTURAL CHANGES IN THE SENSORY GANGLIA OF THE SPINAL NERVES AFTER REPEATED MAGNETIC STIMULATION ON THE MODEL OF ISCHEMIC MYELOPATHY. Morphology, 2013, 143(2): 024-029 DOI:10.17816/morph.398606

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Акимов Г. А. и Семенова-Тян-Шанская В. В. Исследование патоморфологических изменений в нервной системе по методу Б. С. Дойникова. Арх. пат. 1953, т. 15, № 5, с. 82–86.

[2]

Искра Д. А. Периферическая деафферентация при очаговых поражениях центральной нервной системы (особенности патогенеза, клиники, диагностики и лечения двигательных расстройств): Автореф. дис. … д-ра мед. наук. СПб., 2007.

[3]

Миронов А. А., Комиссарчик Я. Ю. и Миронов В. А. Методы электронной микроскопии в биологии и медицине. СПб., Наука, 1995.

[4]

Скоромец А. А., Тиссен Т. П., Панюшкин А. И. и Скоромец Т. А. Сосудистые заболевания спинного мозга. СПб., СОТИС, 1998.

[5]

Cardenas-Morales L. Nowak D. A. and Kammer T. et al. Mechanisms and applications of theta-burst rTMS on the human motor cortex. Brain Topogr., 2010, v. 22, p. 294–306.

[6]

Ridding M. C. and Ziemann U. Determinants of the induction of cortical plasticity by non-invasive brain stimulation in healthy subjects. J. Physiol., 2010, v. 588, № 13, р. 2291–2304.

[7]

Rossi S., Hallett М., Rossini P. M. and Pascual-Leone A. Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clin. Neurophysiol., 2009, v. 120, № 12, р. 2008–2039.

[8]

Tadahiko A. Microangiographic study of the influence of kyphosis on the system of anterior vertebral artery in cases of kyphosis in two-legged rats. J. Korean med. soc., 1989, v. 20, № 1, р. 23–33.

RIGHTS & PERMISSIONS

Eco-Vector

AI Summary AI Mindmap
PDF

65

Accesses

0

Citation

Detail

Sections
Recommended

AI思维导图

/