EFFECT OF TOTAL SIALOADENECTOMY ON THE STRUCTURE OF RAT TESTIS

Abstract

The effect of the major salivary gland removal on the structure of the testes was studied in immature (n=120) and adult (n=120) rats. Testes of intact (n=40), sham-operated (n=40) and sialoadenectomized (n=40) animals were examined at weeks 1, 2, 3, 4, 6, 8, 10 and 12 of the experiment by histological and morphometric methods. In the early stages (up to 6 weeks) after total sialoadenectomy, the multinucleated spermatids and dying cells were observed in the seminiferous epithelium. The diameter of the convoluted seminiferous tubules and spermatogenesis index were decreased. These changes were more pronounced but sooner leveled in mature rats.

Keywords

submandibular gland / testis / seminiferous epithelium

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