POSTNATAL MORPHOGENESIS OF PURKINJE CELLS IN RAT CEREBELLUM

Abstract

Using electron microscopical and histochemical methods, the development of the organelles was examined quantitatively in the cerebellar Purkinje cells of the outbred rats (n=36) in the postnatal period of ontogenesis (Days 2, 7, 15, 45). The study has demonstrated a decrease of nuclear-cytoplasmic ratio, an increase of the nucleolar area, enlargement and lengthening of mitochondria, an increase of the number of membrane-bound ribosomes and of the length of rough endoplasmic reticulum cisterns, an increase in the number and size of lysosomes and the relative area they occupy in the sections of cell cytoplasm.

Keywords

cerebellum / Purkinje cell / ultrastructure / morphometry

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