ANALYSIS OF FACIAL AND HEAD SOFT TISSUE PROPORTION INDICES IN ADULT PATIENTS WITH β-THALASSAEMIA MAJOR

R. V. Shadlinskaya; N. N. Sultanova

doi:10.17816/morph.101896

Morphology ›› 2019, Vol. 156 ›› Issue (4) : 91 -98. DOI: 10.17816/morph.101896

Articles

research-article

ANALYSIS OF FACIAL AND HEAD SOFT TISSUE PROPORTION INDICES IN ADULT PATIENTS WITH β-THALASSAEMIA MAJOR

Author information +

History +

PDF

Abstract

Objective - quantitative analysis of the soft tissues of the head and face in adult patients with β-thalassemia major, using the indices of proportions of the craniofacial complex. Material and methods. The anthropometric data on soft tissues of the head and face were studied in 34 patients with β-thalassemia major: 16 men (average age 23,3±0,9) and 18 women (average age 21,8±1,5). To describe the craniofacial characteristics of the subjects, 40 indices of the proportions of the head and face were calculated according to L. Farkas’s method. The average values of the indices were compared with the data of the norms of a healthy group of people identical in sex, age and ethnic origin. Results. A quantitative analysis of the soft tissues of the head and face of patients with β-thalassemia major revealed a significant difference in the 29 parameters causing the development of craniofacial changes in males and in 24 parameters in females. These patients are characterized by an increase in the transverse head measurements, narrowing of the mandible, shortening of the ramus of mandible, flattening of the nose bridge, narrowing of the root of nose, orbital hypertelorism, protrusion of the orbits, protrusion of the vertical contour of the upper lip. Conclusion. The calculation of head and face proportion indices is of great importance in the planning of treatment of patients with β-thalassemia major.

Keywords

thalassemia / anthropometry / soft tissues of the face / maxillofacial deformities / proportion indices

Cite this article

Download citation ▾

R. V. Shadlinskaya, N. N. Sultanova. ANALYSIS OF FACIAL AND HEAD SOFT TISSUE PROPORTION INDICES IN ADULT PATIENTS WITH β-THALASSAEMIA MAJOR. Morphology, 2019, 156(4): 91-98 DOI:10.17816/morph.101896

登录浏览全文

4963

注册一个新账户忘记密码

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Гланц С. Т. Медико-биологическая статистика: Перевод с англ. / Под ред. Н. Е. Бузикашвили, Д. В. Самойлова. М.: Практика, 1999. 200 c.

[2]	Данилова Д. В. История развития методов изучения формы и пропорций лица человека // Современная стоматология. 2002. № 4. С. 48-51.

[3]	Кармалькова Е. А., Третьякова Т. В., Белевич В. Н. Лицо человека // Военная медицина. 2012. № 4. С. 33-38.

[4]	Abu Alhaija E. S., Hattab F.N., Al-Omari M. A. Cephalometric measu rements and facial deformities in subjects with β-thalassaemia major // Eur. J. Orthodon. 2002. Vol. 24, № 1. P. 9-19.

[5]	Alireza J., Samaneh B., Mahsa M. Investigating the relationship between major thalassemia diseases with anthropometric sizes of head and facial soft tissue // J. Biosci. Biotech. Res. Com. 2017. Vol. 10, № 2. P. 233-240.

[6]	Amini F., Borzabadi-Farahani A., Mashayekhi Z. Soft-tissue profile characteristics in children with beta thalassemia major // Acta Odontol. Scand. 2013. Vol. 71, № 5. P. 1071-1076.

[7]	Asadov C. Immunologic Abnormalities in β-Thalassemia // J. Blood Dis. Transf. 2014. № 5. Р. 224.

[8]	Başsimitçi Ş., Yücel-Eroğlu E., Akalar M. Effects of Thalassaemia Major on Components of the Craniofacial Complex // Brit. J. Orthod. 1996. Vol. 23, № 2. P. 157-162.

[9]	Farkas L., Munro I. Anthropometric Facial Proportions in Meditsina, Charles C Thomas, Springfield, Illinois, 1987. 344 p.

[10]	Galanello R., Origa R. Beta-thalassemia // Orphanet. J. Rare Dis. 2010. № 5. P. 5-11.

[11]	Girinath P., Vahanwala S., Krishnamurthy V., Pagare S. Evaluation of Orofacial Manifestations in 50 Thalassemic Patients: A Clinical Study // J. Ind. Acad. Oral. Med. Radiol. 2012. № 22, № 3. Р. 126-132.

[12]	Wong P., Fuller P. J., Gillespie M. T., Milat F. Bone Disease in Thalassemia: A Molecular and Clinical Overview // Endocrine Rev. 2016. Vol. 37, № 4. P. 320-346.

[13]

Farkas L. G., Katic M. J., Forrest C. R., Alt K. W., Bagic I., Baltadjiev G., Cunha E., Cvicelová M., Davies S., Erasmus I., Gillett-Netting R., Hajnis K., Kemkes-Grottenthaler A., Khomyakova I., Kumi A., Kgamphe J. S., Kayodaigo N., Le T., Malinowski A., Negasheva M., Manolis S., Ogetürk M., Parvizrad R., Rösing F., Sahu P., Sforza C., Sivkov S., Sultanova N., Tomazo-Ravnik T., Tóth G., Uzun A., Yahia E. International anthropometric study of facial morphology in various ethnic groups/races // J. Craniofac. Surg. 2005. Vol. 16, № 4. Р. 615- 646.

[14]	Toman H., Nasir A., Hassan R. Skeletal, dentoalveolar, and soft tissue cephalometric measurements of Malay transfusion-dependent thalassaemia patients // Eur. J. Orthodon. 2011. Vol. 33, № 6. P. 700-704.