Pathogenetic treatment of gunshot wounds of extremities
G. A. Kesyan , A. F. Lazarev , I. E. Kondratiev , G. N. Verchenko , R. Z. Urazgildeev , V. N. Chelyapov
N.N. Priorov Journal of Traumatology and Orthopedics ›› 2001, Vol. 8 ›› Issue (2) : 30 -33.
Pathogenetic treatment of gunshot wounds of extremities
Various unknown appropriateness to the development of gunshot wound process were determined on the base of systemic approach. The causes and mechanisms of complication development were detected as well. Several new treatment methods were elaborated, evaluated in experiment and implemented into clinical practice. Addition of antioxydants to the treatment protocol decreased genotoxic effect and the use of elaborated prognosis for the complication development enabled to decrease the rate of purulent complications up to 5.6%.
experimental studies / genotoxic effect / immunophysiological characteristics
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