Pathophysiological mechanisms of the consequences of trauma of the musculoskeletal system
V. A. Epifanov , A. V. Epifanov
N.N. Priorov Journal of Traumatology and Orthopedics ›› 2001, Vol. 8 ›› Issue (1) : 62 -65.
Pathophysiological mechanisms of the consequences of trauma of the musculoskeletal system
In the most general form, the main factors of traumatic disease can be represented as follows (Scheme 1): the traumatic factor acts on organs and tissues, causing their damage. As a result of this, the cells are destroyed and their contents are released into the intercellular environment; other cells are exposed to concussion, as a result of which their metabolism and their inherent functions are disturbed. Primarily (as a result of the action of a traumatic factor) and secondarily (due to a change in the tissue environment), numerous receptors in the wound are irritated, which is subjectively perceived as pain, and objectively characterized by numerous reactions of organs and systems.
traumatic factor / violation of afferentation / proprioceptors
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