Surgical Treatment of Ledderhose Disease in Patient with Mucopolysaccharidosis Type I (Hurler-Sheie)

Abstract

Case report of a 29 years old female patient with mucopolysaccharidosis type I and Ledderhose disease is presented. Examination of plantar surfaces showed tumor like protrusions up to 6.5 cm, of irregular shape and extremely painful at palpation, on both feet. Resection of plantar aponeurosis and fibrotic nodes on both feet was performed against a background of pathogenetic enzyme replacement therapy. No complications were observed in postoperative period. This case illustrates that in such patients performance of early surgical intervention at specialized departments is possible and reasonable, as it enables to restore weight bearing ability of the foot as well as significantly increases the quality of life.

Keywords

mucopolysaccharidosis / plantar aponeurosis / Ledderhose disease / surgery

References

[1] Ledderhose G. Uber Zerreissungen der Plantarfascie Archiv fur Klinische Chirurgie. 1894; 48: 853-6.

[2] Матяшин И.М., Ольшанский А.А., Глузман А.М. Симптомы и синдромы в хирургии. Киев: Здоровья; 1975.

[3] Волков М.В., Меерсон Е.М., Нечволодова О.Л., Самойлова Л. И., Юкина Г.П. Наследственные системные заболевания скелета. М.: Медицина; 1982.

[4] Козлова С.И., Демикова Н.С. Наследственные синдромы и медико-генетическое консультирование: Атлас-справочник. 3-е изд., перераб. и дополненное. М.: Авторская академия; 2007.

[5] Пащук А.Ю. Регионарное обезболивание. М.: Медицина; 1987.

RIGHTS & PERMISSIONS

Eco-Vector