Experimental model of hereditary spinal deformity
A. M. Zaydman , P. M. Borodin , T. V. Rusova , A. V. Korel , A. V. Sakharov
N.N. Priorov Journal of Traumatology and Orthopedics ›› 2003, Vol. 10 ›› Issue (4) : 69 -73.
Experimental model of hereditary spinal deformity
Model of spine deformity-like Sheuermann—Mau disease was obtained by crossing of two lines of mice with known genetic defects. Results of morphologic and ultrastructural studies permitted to extra-polate the obtained data, with certain prudence, on clinical manifestations of investigated pathology and to explain the main pathogenic mechanisms of process development.
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