Oxyprolinuria and Glycosaminoglycansuria in Achilles Tendon Ruptures

Abstract

In 17 athlets and ballet dancers with Achilles tendon ruptures oxyprolinuria and urine content of hexuronic acid were studied. Considerable increase of collagen and glycosaminoglycans decay products was detected. The results of differential spectrophotometry showed that urine glycosaminoglycanes presented by proteoglycans. It was assumed that Achilles tendon ruptures could be caused by excessive mechanical load and/or lack of the connective tissue metabolism. The authors consider that further study of oxyprolinuria as well as enzyme-substrate systems of glycosaminoglycans are perspective for the detection of «trauma risk group».

Keywords

oxyproline / glycosaminoglycans / Achilles tendon / hexuronic acids / collagen

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