The empiric antibacterial therapy of postpartum endometritis

Abstract

The purpose of study. To ameliorate results of treatment of postpartum endometritis if puerperals labored in Moscow as a result of prescription of effective empiric antibacterial therapy Material and methods. The sampling of 50 puerperals with endometritis as complication during postpartum period was examined. In all female patients, the inoculation of secretion of uterine cavity was taken and successive determination of sensitivity to antibacterial pharmaceuticals was applied using agar diffusion method. The results. In all inoculations in diagnostic significant titers (≥105 CFU/ml), in overwhelming majority of cases the associations of microorganisms were secured where leading positions occupied by Enterococcus faecalis and faecium, Escherichia coli and Staphylococcus aureus. Conclusion. The Amoxicillin/Clavulanic acid is pharmaceutical of choice in treatment of postpartum endometritis of average degree of severity. The combination of Levofloxacin and Metronidazole is an alternative scheme of treatment of postpartum endometritis of average degree of severity. Under severe endometritis with syndrome of systemic inflammatory reaction carbapenems are pharmaceuticals of choice.

Keywords

puerperals / postpartum endometritis / antibacterial therapy

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